Remodeling of the left ventricle in primary aldosteronism due to Conn's adenoma

GP Rossi, A Sacchetto, E Pavan, P Palatini… - Circulation, 1997 - Am Heart Assoc
Background Since hyperaldosteronism has been experimentally related to myocardial
interstitial fibrosis, we investigated the effects of hypertension and excess aldosterone due to …

Role of aldosterone in left ventricular hypertrophy in hypertension

K Matsumura, K Fujii, H Oniki, M Oka… - American journal of …, 2006 - academic.oup.com
Background: Aldosterone induces cardiac fibrosis in experimental animal models, but only
limited information is available on the association between aldosterone and left ventricular …

Adrenalectomy reverses myocardial fibrosis in patients with primary aldosteronism

YH Lin, XM Wu, HH Lee, JK Lee, YC Liu… - Journal of …, 2012 - journals.lww.com
Objective: Primary aldosteronism is the most frequent cause of secondary hypertension and
is associated with more prominent left ventricular hypertrophy and increased myocardial …

Changes in left ventricular anatomy and function in hypertension and primary aldosteronism

GP Rossi, A Sacchetto, P Visentin, C Canali… - …, 1996 - Am Heart Assoc
We investigated the effects on the heart of hypertension due to the excess of aldosterone
and suppression of the renin-angiotensin system caused by primary aldosteronism with M …

Excess ldosterone is associated with alterations of myocardial texture in primary aldosteronism

GP Rossi, V Di Bello, C Ganzaroli, A Sacchetto… - …, 2002 - Am Heart Assoc
Hyperaldosteronism has been causally linked to myocardial interstitial fibrosis
experimentally, but it remains unclear if this link also applies to humans. Thus, we …

Evidence for an increased rate of cardiovascular events in patients with primary aldosteronism

P Milliez, X Girerd, PF Plouin, J Blacher… - Journal of the American …, 2005 - jacc.org
Objectives: The aim of this report was to show that the rate of cardiovascular events is
increased in patients with either subtype of primary aldosteronism (PA). Background …

Renal damage in primary aldosteronism: results of the PAPY Study

GP Rossi, G Bernini, G Desideri, B Fabris, C Ferri… - …, 2006 - Am Heart Assoc
Primary aldosteronism (PA) has been associated with cardiovascular hypertrophy and
fibrosis, in part independent of the blood pressure level, but deleterious effects on the …

Cortisol excess in patients with primary aldosteronism impacts left ventricular hypertrophy

C Adolf, A Köhler, A Franke, K Lang… - The Journal of …, 2018 - academic.oup.com
Context Primary aldosteronism (PA) represents the most frequent form of endocrine
hypertension. Hyperaldosteronism and hypercortisolism both induce excessive left …

Aldosterone as a key mediator of the cardiometabolic syndrome in primary aldosteronism: an observational study

G Giacchetti, V Ronconi, F Turchi… - Journal of …, 2007 - journals.lww.com
Objective Primary aldosteronism (PA) is characterized by the onset of both cardiac and
gluco-metabolic alterations. The aim of this study was to evaluate the impact of aldosterone …

Cardiac remodeling in patients with primary and secondary aldosteronism: a tissue Doppler study

M Cesari, C Letizia, P Angeli, S Sciomer… - Circulation …, 2016 - Am Heart Assoc
Background—Primary aldosteronism (PA) causes excess left ventricular (LV) hypertrophy
and diastolic dysfunction; whether this occurs also in secondary aldosteronism (SA) without …