[HTML][HTML] Beta-sitosterol as a promising anticancer agent for chemoprevention and chemotherapy: Mechanisms of action and future prospects

H Wang, Z Wang, Z Zhang, J Liu, L Hong - Advances in Nutrition, 2023 - Elsevier
Cancer is one of the primary causes of death worldwide and its incidence continues to
increase year by year. Despite significant advances in research, the search for effective and …

Beta-sitosterol: a promising but orphan nutraceutical to fight against cancer

MS Bin Sayeed, SS Ameen - Nutrition and cancer, 2015 - Taylor & Francis
All the currently available cancer therapeutic options are expensive but none of them are
safe. However, traditional plant-derived medicines or compounds are relatively safe. One …

[HTML][HTML] Molecular mechanism of β-sitosterol and its derivatives in tumor progression

X Bao, Y Zhang, H Zhang, L Xia - Frontiers in oncology, 2022 - frontiersin.org
β-Sitosterol (SIT), a white powdery organic substance with a molecular formula of C29H50O,
is one of the most abundant naturally occurring phytosterols in plants. With a chemical …

Multifunctional roles and pharmacological potential of β-sitosterol: Emerging evidence toward clinical applications

Z Khan, N Nath, A Rauf, TB Emran, S Mitra… - Chemico-biological …, 2022 - Elsevier
Currently, available therapeutic medications are both costly as well as not entirely promising
in terms of potency. So, new candidates from natural resources are of research interest to …

[PDF][PDF] Taraxasterol and b-sitosterol: new naturally compounds with chemoprotective/chemopreventive effects Minireview

Z Ovesnaâ, AV Lkovaâ, KH Thovaâ - Neoplasma, 2004 - researchgate.net
Substantial attention has been given to primary cancer prevention in daily life. Dietary
factors are through to contribute to as much as one-third of the factors influencing the …

β-Sitosterol inhibits cell growth and induces apoptosis in SGC-7901 human stomach cancer cells

Y Zhao, SKC Chang, G Qu, T Li… - Journal of agricultural and …, 2009 - ACS Publications
β-Sitosterol is an important phytosterol found in plant food. It has been shown to have
antiproliferative effects on cancers of the colon, breast, and prostate, but its effect on …

Apoptotic effect of a phytosterol-ingredient and its main phytosterol (β-sitosterol) in human cancer cell lines

A Alvarez-Sala, A Attanzio, L Tesoriere… - … journal of food …, 2019 - Taylor & Francis
Dietary interventions may effectively control cancer development, with phytosterols (PS)
being a class of cancer chemopreventive dietary phytochemicals. The present study, for the …

Phytosterols as a natural anticancer agent: Current status and future perspective

N Shahzad, W Khan, MD Shadab, A Ali… - Biomedicine & …, 2017 - Elsevier
Phytosterols are naturally occurring compounds in plants, structurally similar to cholesterol.
The human diet is quite abundant in sitosterol and campesterol. Phytosterols are known to …

Phytosterols in cancer: from molecular mechanisms to preventive and therapeutic potentials

F Blanco-Vaca, L Cedó, J Julve - Current Medicinal Chemistry, 2019 - ingentaconnect.com
Cancer is the second leading cause of death worldwide. Compelling evidence supports the
hypothesis that the manipulation of dietary components, including plant compounds termed …

Phytosterols as anticancer compounds

PG Bradford, AB Awad - Molecular nutrition & food research, 2007 - Wiley Online Library
Phytochemicals have been proposed to offer protection against a variety of chronic ailments
including cardiovascular diseases, obesity, diabetes, and cancer. As for cancer protection, it …