Early embryonic arrest and fragmentation (EEAF) is a common phenotype observed in in
vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) cycles. The phenotype …

Early embryonic arrest and fragmentation (EEAF) is a common phenomenon leading to
female infertility, but the genetic determinants remain largely unknown. The Moloney …

Background oocyte maturation arrest (OMA) is currently one of the major causes of in vitro
fertilization (IVF) failure, and several gene mutations were found to be associated with OMA …

STUDY QUESTION Are mutations in MOS (MOS proto-oncogene, serine/threonine kinase)
involved in early embryonic arrest in infertile women? SUMMARY ANSWER We identified …

STUDY QUESTION What is the genetic basis of female infertility involving abnormal oocyte
morphology with the production of a large first polar body (PB1)? SUMMARY ANSWER The …

Assisted reproduction procedures often encounter an issue called oocyte maturation arrest
(OMA), which is manifested as failed IVF/ICSI attempts using oocytes from some infertile …

Purpose Poor ovarian response (POR) affects approximately 9% to 24% of women
undergoing in vitro fertilization (IVF) cycles, resulting in fewer eggs obtained and increasing …

BACKGROUND Infertility and pregnancy loss are longstanding problems. Successful
fertilization and high-quality embryos are prerequisites for an ongoing pregnancy. Studies …

Early embryonic arrest (EEA) is a critical impediment in assisted reproductive technology
(ART), affecting 40% of infertile patients by halting the development of early embryos from …

Many clinical studies have shown that embryos of in vitro fertilization (IVF) are often prone to
developmental arrest, which leads to recurrent failure of IVF treatment. Early embryonic …