2-pyridones represents ubiquitous scaffolds often present in both natural products and
pharmaceutical compounds. Due to their wide applications in medicinal chemistry, it is not …

Owing to the versatile applications in different areas including biology, natural compounds,
dyes, and fluorescent materials, the synthesis of 2-pyridone compounds is an important …

2-Pyridone-containing heterocycles are considered privileged scaffolds in drug discovery
due to their behavior as hydrogen bond donors and/or acceptors and nonpeptidic mimics …

Pyridone core structure has attracted much attention due to its abundance in natural
products of biological importance. 2-Pyridone derivatives display diverse biological …

Multicomponent reactions (MCRs) have emerged as key green tool in organic synthesis for
their methodological simplicity. MCRs have made heterocycle synthesis more versatile. The …

This microreview focuses on the methodologies for the synthesis of 2-pyridones and their
biological applications. Various types of synthetic methods reported in the last 6 years …

Efficient and divergent one-pot synthesis of polyfunctionalized 2-pyridones from β-keto
amides based on reaction condition selection was developed. The methodology offers …

A protocol has been developed for the efficient synthesis of structurally diverse 3, 4-
dihydropyridin-2 (1 H)-ones and 3, 4-dihydro-2 H-pyrans via four-component reactions of …

2, 4, 6-Triarylpyridines are key building blocks to access functional molecules that are used
in the design of advanced materials, metal–organic frameworks, supramolecules, reactive …

A domino strategy has been used for the synthesis of 2H-pyrido [1, 2-a] pyrimidin-2-ones.
Four sequential reactions: aza-Michael addition, water elimination, intramolecular acyl …