Maternal MTHFR 677C>T, 1298A>C gene polymorphisms and risk of offspring aneuploidy

O Miljanović, S Teofilov, M Anđelić, Z Magić… - Prenatal …, 2022 - Wiley Online Library
Objective The objective was to investigate the association between maternal
methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms, crucial for DNA …

Associations between maternal methylenetetrahydrofolate reductase polymorphisms and adverse outcomes of pregnancy: the Hordaland Homocysteine Study

E Nurk, GS Tell, H Refsum, PM Ueland… - The American journal of …, 2004 - Elsevier
PURPOSE: Methylenetetrahydrofolate reductase (MTHFR) is involved in the metabolism of
folate and homocysteine; a polymorphism in the MTHFR gene (677C→ T) has been …

Methylenetetrahydrofolate reductase C677T polymorphism and pregnancy complications

F Stonek, E Hafner, K Philipp, LA Hefler… - Obstetrics & …, 2007 - journals.lww.com
OBJECTIVE: To investigate the frequency of the methylenetetrahydrofolate reductase
(MTHFR) C677T polymorphism in women with intrauterine fetal death, preeclampsia …

The association between maternal methylenetetrahydrofolate reductase C677T and A1298C polymorphism and birth defects and adverse pregnancy outcomes

Y Zhang, X He, X Xiong, J Chuan, L Zhong… - Prenatal …, 2019 - Wiley Online Library
Published studies indicate the MTHFR C677T and A1298C polymorphisms are associated
with abnormal homocysteine levels, which may cause various pregnancy complications and …

Determining the association between methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms and genomic DNA methylation level: a meta‐analysis

L Wang, S Shangguan, S Chang, X Yu… - … Research Part A …, 2016 - Wiley Online Library
Background The methylenetetrahydrofolate reductase (MTHFR) polymorphism is a risk
factor for neural tube defects. C677T and A1298C MTHFR polymorphisms produce an …

No evidence for association of MTHFR 677C>T and 1298A>C variants with placental DNA methylation

GF Del Gobbo, EM Price, CW Hanna, WP Robinson - Clinical Epigenetics, 2018 - Springer
Abstract Background 5, 10-Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme
in one-carbon metabolism that ensures the availability of methyl groups for methylation …

Association between maternal, fetal and paternal MTHFR gene C677T and A1298C polymorphisms and risk of recurrent pregnancy loss: a comprehensive evaluation

Y Yang, Y Luo, J Yuan, Y Tang, L Xiong, MM Xu… - Archives of gynecology …, 2016 - Springer
Purpose Numerous studies have investigated the associations between
methylenetetrahydrofolate reductase (MTHFR) gene C677T and A1298C polymorphisms …

Methylenetetrahydrofolate reductase polymorphisms and pregnancy outcome

M Turgal, F Gumruk, E Karaagaoglu… - Geburtshilfe und …, 2018 - thieme-connect.com
Introduction Aim of the study was to evaluate the effect of methylenetetrahydrofolate
reductase (MTHFR) polymorphisms on pregnancy outcome. Materials and Methods A total …

[HTML][HTML] Association of maternal and fetal MTHFR A1298C polymorphism with the risk of pregnancy loss: a study of an Indian population and a meta-analysis

RR Nair, A Khanna, R Singh, K Singh - Fertility and sterility, 2013 - Elsevier
OBJECTIVE: To study the genetic association between methylenetetrahydrofolate reductase
(MTHFR) A1298 polymorphism and recurrent pregnancy loss (RPL). DESIGN: Prospective …

[HTML][HTML] Maternal methylenetetrahydrofolate reductase (MTHFR) A1298C polymorphism: implications in preventing recurrent pregnancy loss

S Jose - Journal of Preventive Medicine and Hygiene, 2024 - ncbi.nlm.nih.gov
Discussion DNA methylation is a crucial aspect of epigenetics that plays a vital role in
cellular growth, differentiation, and the development of various human disorders. The …