Exploiting breakdown in nonhost effector–target interactions to boost host disease resistance
H McLellan, SE Harvey… - Proceedings of the …, 2022 - National Acad Sciences
Plants are resistant to most microbial species due to nonhost resistance (NHR), providing
broad-spectrum and durable immunity. However, the molecular components contributing to …
broad-spectrum and durable immunity. However, the molecular components contributing to …
RxLR effectors: Master modulators, modifiers and manipulators
S Wang, H McLellan, PC Boevink… - Molecular Plant …, 2023 - Am Phytopath Society
Cytoplasmic effectors with an Arg-any amino acid-Arg-Leu (RxLR) motif are encoded by
hundreds of genes within the genomes of oomycete Phytophthora spp. and downy mildew …
hundreds of genes within the genomes of oomycete Phytophthora spp. and downy mildew …
Convergent targeting of a common host protein-network by pathogen effectors from three kingdoms of life
R Weßling, P Epple, S Altmann, Y He, L Yang… - Cell host & …, 2014 - cell.com
While conceptual principles governing plant immunity are becoming clear, its systems-level
organization and the evolutionary dynamic of the host-pathogen interface are still obscure …
organization and the evolutionary dynamic of the host-pathogen interface are still obscure …
Target the core: durable plant resistance against filamentous plant pathogens through effector recognition
JRL Depotter, G Doehlemann - Pest Management Science, 2020 - Wiley Online Library
Plant pathogens colonize their host through the secretion of effector proteins that modulate
plant metabolism and immune responses to their benefit. Plants evolve towards effector …
plant metabolism and immune responses to their benefit. Plants evolve towards effector …
From effectors to effectomes: Are functional studies of individual effectors enough to decipher plant pathogen infectious strategies?
N Arroyo-Velez, M González-Fuente, N Peeters… - PLoS …, 2020 - journals.plos.org
Effector proteins of plant pathogens are key virulence determinants which can be secreted in
the apoplast or translocated inside plant cells where they subvert host immunity and …
the apoplast or translocated inside plant cells where they subvert host immunity and …
Effector biology in focus: a primer for computational prediction and functional characterization
RJD Dalio, J Herlihy, TS Oliveira… - Molecular Plant …, 2018 - Am Phytopath Society
Plant–pathogen interactions are controlled by a multilayered immune system, which is
activated by pathogen recognition in the host. Pathogens secrete effector molecules to …
activated by pathogen recognition in the host. Pathogens secrete effector molecules to …
Host-interactor screens of Phytophthora infestans RXLR proteins reveal vesicle trafficking as a major effector-targeted process
Pathogens modulate plant cell structure and function by secreting effectors into host tissues.
Effectors typically function by associating with host molecules and modulating their activities …
Effectors typically function by associating with host molecules and modulating their activities …
Phytophthora parasitica Effector PpRxLR2 Suppresses Nicotiana benthamiana Immunity
RJD Dalio, HJ Maximo, TS Oliveira… - Molecular Plant …, 2018 - Am Phytopath Society
Phytophthora species secrete several classes of effector proteins during interaction with
their hosts. These proteins can have multiple functions including modulation of host …
their hosts. These proteins can have multiple functions including modulation of host …
A Phytophthora infestans RXLR effector targets plant PP1c isoforms that promote late blight disease
Plant pathogens deliver effectors to alter host processes. Knowledge of how effectors target
and manipulate host proteins is critical to understand crop disease. Here, we show that in …
and manipulate host proteins is critical to understand crop disease. Here, we show that in …
Potato NPH3/RPT2-Like Protein StNRL1, Targeted by a Phytophthora infestans RXLR Effector, Is a Susceptibility Factor
L Yang, H McLellan, S Naqvi, Q He… - Plant …, 2016 - academic.oup.com
Plant pathogens deliver effectors to manipulate host processes. We know little about how
fungal and oomycete effectors target host proteins to promote susceptibility, yet such …
fungal and oomycete effectors target host proteins to promote susceptibility, yet such …