The fall and rise of pharmacology–(Re-) defining the discipline?

RJ Winquist, K Mullane, M Williams - Biochemical Pharmacology, 2014 - Elsevier
Pharmacology is an integrative discipline that originated from activities, now nearly 7000
years old, to identify therapeutics from natural product sources. Research in the 19th …

Challenges facing pharmacology–the in vivo situation

MJA Walker, MLM Soh - Trends in pharmacological sciences, 2006 - cell.com
There is concern among pharmacologists [1] about the growing loss of skills in
pharmacological sciences. Although this concern is expressed at various levels [2], it is of …

Translational paradigms in pharmacology and drug discovery

K Mullane, RJ Winquist, M Williams - Biochemical Pharmacology, 2014 - Elsevier
The translational sciences represent the core element in enabling and utilizing the output
from the biomedical sciences and to improving drug discovery metrics by reducing the …

Understanding pharmacology in humans: Phase I and Phase II (data generation)

EM Pich - Current opinion in pharmacology, 2011 - Elsevier
The discovery of novel drugs is a complex and highly regulated process organized around a
critical moment, that is, when the novel compound is tested in humans. This process …

Defining the role of pharmacology in the emerging world of translational research

SJ Enna, M Williams - Advances in pharmacology, 2009 - Elsevier
Pharmacology is focused on studying the effects of endogenous agents and xenobiotics on
tissue and organ function. Analysis of the concentration/response relationship is the …

Clinical pharmacology as a foundation for translational science.

SA Waldman, RJ Hohl, GL Kearns, SJ Swan, A Terzic - 2011 - jdc.jefferson.edu
The evolution of enabling technologies and their associated perspectives into molecular
mechanisms underlying disease has extended beyond the abilities of scientific and clinical …

[图书][B] Pharmacology: principles and practice

M Hacker, WS Messer, KA Bachmann - 2009 - books.google.com
Pharmacology meets the rapidly emerging needs of programs training pharmacologic
scientists seeking careers in basic research and drug discovery rather than such applied …

What is the future role of pharmacologists in the pharmaceutical industry?

MG Collis - Trends in pharmacological sciences, 2006 - cell.com
What is the future role of pharmacologists in the pharmaceutical industry? the fact that
biological reality, as a result of its evolutionary complexity and many interactive terms, defies …

Pharmaceutical sciences in the next millennium

DJ Triggle - Annals of Pharmacotherapy, 1999 - journals.sagepub.com
All of these factors are important and all will mutually interact. This presentation will,
however, focus on only one factor, the impact of scientific development and, specifically, the …

The revolution of pharmaco-omics: ready to open new avenues in materializing precision medicine?

G Ragia, VG Manolopoulos - Pharmacogenomics, 2022 - Taylor & Francis
Full article: The Revolution of Pharmaco-Omics: Ready to Open new Avenues in
Materializing Precision Medicine? Skip to Main Content Taylor and Francis Online …