Total Synthesis of Bryostatin 7 via C–C Bond-Forming Hydrogenation

Y Lu, SK Woo, MJ Krische - Journal of the American Chemical …, 2011 - ACS Publications
Total Synthesis of Bryostatin 7 via C–C Bond-Forming Hydrogenation | Journal of the American
Chemical Society ACS ACS Publications C&EN CAS Find my institution Log In Journal of the …

Total synthesis of bryostatin 2

DA Evans, PH Carter, EM Carreira… - Journal of the …, 1999 - ACS Publications
The total synthesis of the marine macrolide bryostatin 2 is described. The synthesis plan
relies on aldol and directed reduction steps in order to construct the anti-1, 3-diol array …

Total synthesis of bryostatin 1

GE Keck, YB Poudel, TJ Cummins… - Journal of the …, 2011 - ACS Publications
Bryostatin 1 is a marine natural product that is a very promising lead compound because of
the potent biological activity it displays against a variety of human disease states. We …

Total synthesis of bryostatin 3

BM Trost, Y Wang, AK Buckl, Z Huang, MH Nguyen… - Science, 2020 - science.org
Bryostatins are a family of 21 complex marine natural products with a wide range of potent
biological activities. Among all the 21 bryostatins, bryostatin 3 is structurally the most …

Asymmetric synthesis of the C (10) C (16) segment of the bryostatins

TFJ Lampe, HMR Hoffmann - Tetrahedron letters, 1996 - Elsevier
PII: 0040-4039(96)01759-5 Page 1 Pergamon Tetrahedron Letters, Vol. 37, No. 43, pp. 7695-7698,
1996 Copyright O 1996 Elsevier Science Ltd Printed in Great Britain. All rights reserved PH …

Total synthesis of bryostatin 9

PA Wender, AJ Schrier - Journal of the American Chemical …, 2011 - ACS Publications
Total Synthesis of Bryostatin 9 | Journal of the American Chemical Society ACS ACS
Publications C&EN CAS Find my institution Log In Journal of the American Chemical …

Synthetic studies toward the Bryostatins: a substrate-controlled approach to the A-ring

GE Keck, DS Welch, PK Vivian - Organic letters, 2006 - ACS Publications
Synthetic Studies toward the Bryostatins: A Substrate-Controlled Approach to the A-Ring |
Organic Letters ACS ACS Publications C&EN CAS Find my institution Log In Organic Letters …

Total synthesis of bryostatin 1: A short route

S Manaviazar, KJ Hale - Angewandte Chemie International Edition, 2011 - infona.pl
A chemical legacy: Keck and his team have chemically pursued the bryostatin 1 structure
with great vigor in recent years and, in late 2010, they finally completed their quest of …

Total Syntheses of Bryostatins: Synthesis of Two Ring‐Expanded Bryostatin Analogues and the Development of a New‐Generation Strategy to Access the C7–C27 …

BM Trost, H Yang, G Dong - Chemistry–A European Journal, 2011 - Wiley Online Library
Herein, we report the synthesis of novel ring‐expanded bryostatin analogues. By carefully
modifying the substrate, a selective and high‐yielding Ru‐catalyzed tandem enyne …

Synthetic studies on the bryostatins: synthetic routes to analogues containing the tricyclic macrolactone core

GE Keck, AP Truong - Organic letters, 2005 - ACS Publications
Synthesis of the first of a projected series of bryostatin analogues has been accomplished in
26 steps and 2.2% overall yield. In this letter, we detail two approaches to the structural core …