Comprehensive pan-cancer analysis identifies the RNA-binding protein LRPPRC as a novel prognostic and immune biomarker
Z Wu, X Liu, F Xie, C Ma, EWF Lam, N Kang, D Jin… - Life Sciences, 2024 - Elsevier
Aims RNA-binding proteins (RBPs) play pivotal roles in carcinogenesis and immunotherapy.
Leucine-rich pentapeptide repeat-containing protein (LRPPRC) is crucial for RNA …
Leucine-rich pentapeptide repeat-containing protein (LRPPRC) is crucial for RNA …
LRPPRC regulates malignant behaviors, protects mitochondrial homeostasis, mitochondrial function in osteosarcoma and derived cancer stem-like cells
Z Zhao, Y Sun, J Tang, Y Yang, X Xu - BMC cancer, 2023 - Springer
Background Leucine-rich pentatricopeptide repeat containing (LRPPRC) is a potential
oncogene in multiple tumor types, including lung adenocarcinoma, esophageal squamous …
oncogene in multiple tumor types, including lung adenocarcinoma, esophageal squamous …
Downregulation of LRP/LR with siRNA inhibits several cancer hallmarks in lung cancer cells
MJ Bignoux, TC Otgaar, M Bernert, SFT Weiss… - FEBS Open …, 2023 - Wiley Online Library
The incidence and mortality rates of cancer are growing rapidly worldwide, with lung cancer
being the most commonly occurring cancer in males. Human carcinomas circumvent the …
being the most commonly occurring cancer in males. Human carcinomas circumvent the …
The characteristic landscape of lncRNAs classified by RBP–lncRNA interactions across 10 cancers
Q Zhang, Y Wei, Z Yan, C Wu, Z Chang, Y Zhu… - Molecular …, 2017 - pubs.rsc.org
RNA-binding proteins (RBPs) are key regulators of gene expression. Some long non-coding
RNAs (lncRNAs) affect gene expression by interacting with RBPs. However, whether this …
RNAs (lncRNAs) affect gene expression by interacting with RBPs. However, whether this …
[HTML][HTML] LRPPRC facilitates tumor progression and immune evasion through upregulation of m6A modification of PD-L1 mRNA in hepatocellular carcinoma
H Wang, A Tang, Y Cui, H Gong, H Li - Frontiers in immunology, 2023 - frontiersin.org
Objective LRPPRC is a newly discovered N6-methyladenosine (m6A) modification reader,
which potentially affects hepatocellular carcinoma (HCC) progression. PD-L1 in tumor cells …
which potentially affects hepatocellular carcinoma (HCC) progression. PD-L1 in tumor cells …
LRP1B: a giant lost in cancer translation
C Príncipe, IJ Dionísio de Sousa, H Prazeres… - Pharmaceuticals, 2021 - mdpi.com
Low-density lipoprotein receptor-related protein 1B (LRP1B) is a giant member of the LDLR
protein family, which includes several structurally homologous cell surface receptors with a …
protein family, which includes several structurally homologous cell surface receptors with a …
Integrated analysis of the functions and prognostic values of RNA binding proteins in lung squamous cell carcinoma
W Li, X Li, LN Gao, CG You - Frontiers in Genetics, 2020 - frontiersin.org
Lung cancer is the leading cause of cancer-related deaths worldwide. Dysregulation of RNA
binding proteins (RBPs) has been found in a variety of cancers and is related to …
binding proteins (RBPs) has been found in a variety of cancers and is related to …
The significance of LRPPRC overexpression in gastric cancer
X Li, L Lv, J Zheng, J Zhou, B Liu, H Chen, C Liang… - Medical Oncology, 2014 - Springer
LRPPRC is a multifunctional protein involved in mitochondrial gene expression and
function, cell cycle progression, and tumorigenesis. We analyzed LRPPRC gene expression …
function, cell cycle progression, and tumorigenesis. We analyzed LRPPRC gene expression …
A comprehensive expression landscape of RNA-binding proteins (RBPs) across 16 human cancer types
ABSTRACT RNA-binding proteins (RBPs) are key regulators of posttranscriptional
processes such as RNA maturation, localization, turnover and translation. Despite their …
processes such as RNA maturation, localization, turnover and translation. Despite their …
RNA-binding proteins in cancer: advances in translational research
C Mancarella, N Bley, LOF Penalva - Frontiers in Cell and …, 2024 - frontiersin.org
RNA-binding proteins (RBPs) regulate RNA metabolism, processing, and translation by
establishing highly dynamic interactions with hundreds of coding and non-coding target …
establishing highly dynamic interactions with hundreds of coding and non-coding target …