Cell spheroids bridge the discontinuity between in vitro systems and in vivo animal models.
However, inducing cell spheroids by nanomaterials remains an inefficient and poorly …

Cell-mediated remodeling of extracellular matrix (ECM) plays important roles for cell
functions, but it is challenging to develop synthetic materials for mimicking such a dynamic …

Intracellular protein filaments are ubiquitous for cellular functions, but forming bona fide
biomimetic intracellular filaments of small molecules in living cells remains elusive. Here, we …

Nature regulates cellular interactions through the cell-surface molecules and plasma
membranes. Despite advances in cell-surface engineering with diverse ligands and reactive …

Like cellular proteins that form fibrillar nanostructures, small hydrogelator molecules self-
assemble in water to generate molecular nanofibers. In contrast to the well-defined (dys) …

Progress in the design and synthesis of nanostructured self-assembling systems has
facilitated the realization of numerous nanoscale geometries, including fibers, ribbons, and …

Recapitulating the elegant structures formed during development is an extreme synthetic
and biological challenge. Great progress has been made in developing materials to support …

Traditional 2-D cell cultures have many limitations because they do not truly mimic the
natural environment. In order to fully understand the in vivo 3-D environment, it is crucial to …

One of the advantages of materials produced by self-assembly is that in principle they can
be formed in any given container to produce materials of predetermined shapes and sizes …

Cell and tissue engineering therapies for regenerative medicine as well as cell‐based
assays require an understanding of the interactions between cells with the surrounding …