Role of microRNAs in tumor progression by regulation of kinesin motor proteins
Aberrant cell proliferation is one of the main characteristics of tumor cells that can be
affected by many cellular processes and signaling pathways. Kinesin superfamily proteins …
affected by many cellular processes and signaling pathways. Kinesin superfamily proteins …
[HTML][HTML] Overexpression of KIF2A is suppressed by miR-206 and associated with poor prognosis in ovarian cancer
N Sheng, YZ Xu, QH Xi, HY Jiang, CY Wang… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: This study aimed to investigate the expression and prognostic value of
kinesin family member 2A (KIF2A) and the suppression effects of microRNA-206 (miR-206) …
kinesin family member 2A (KIF2A) and the suppression effects of microRNA-206 (miR-206) …
KIF2A silencing inhibits the proliferation and migration of breast cancer cells and correlates with unfavorable prognosis in breast cancer
J Wang, S Ma, R Ma, X Qu, W Liu, C Lv, S Zhao… - Bmc Cancer, 2014 - Springer
Background Kinesin family member 2a (KIF2A), a type of motor protein found in eukaryotic
cells, is associated with development and progression of various human cancers. The role of …
cells, is associated with development and progression of various human cancers. The role of …
Pan-cancer analysis of kinesin family members with potential implications in prognosis and immunological role in human cancer
M Zhong, L Gong, N Li, H Guan, K Gong… - Frontiers in …, 2023 - frontiersin.org
Background Kinesin is a molecular motor for transporting “goods” within cells and plays a
key role in many types of tumors. The multi-angle study of kinesin at the pan-cancer level is …
key role in many types of tumors. The multi-angle study of kinesin at the pan-cancer level is …
Down‐regulation of KIF 2A inhibits gastric cancer cell invasion via suppressing MT 1‐MMP
P Zhao, F Lan, H Zhang, G Zeng… - Clinical and Experimental …, 2018 - Wiley Online Library
Gastric cancer accounts for a sizeable proportion of global cancer mortality with high
morbidity and poor prognosis. Kinesin superfamily proteins (KIF s) are microtubule …
morbidity and poor prognosis. Kinesin superfamily proteins (KIF s) are microtubule …
Regulation of KIF2A by Antitumor miR-451a Inhibits Cancer Cell Aggressiveness Features in Lung Squamous Cell Carcinoma
A Uchida, N Seki, K Mizuno, Y Yamada, S Misono… - Cancers, 2019 - mdpi.com
In the human genome, miR-451a is encoded close to the miR-144 on chromosome region
17q11. 2. Our previous study showed that both strands of pre-miR-144 acted as antitumor …
17q11. 2. Our previous study showed that both strands of pre-miR-144 acted as antitumor …
Characterization of kinesin family member 2C as a proto-oncogene in cervical cancer
J Yang, Z Wu, L Yang, JH Jeong, Y Zhu, J Lu… - Frontiers in …, 2022 - frontiersin.org
Kinesin family member 2C (KIF2C) is known as an oncogenic gene to regulate tumor
progression and metastasis. However, its pan-cancer analysis has not been reported. In this …
progression and metastasis. However, its pan-cancer analysis has not been reported. In this …
[HTML][HTML] KIF2A promotes the progression via AKT signaling pathway and is upregulated by transcription factor ETV4 in human gastric cancer
X Zhang, Y Wang, X Liu, A Zhao, Z Yang, F Kong… - Biomedicine & …, 2020 - Elsevier
Kinesin family protein 2A (KIF2A), an M-type nonmotile microtubule depolymerase, plays
essential roles in development and progression of various human cancers. However, its …
essential roles in development and progression of various human cancers. However, its …
KIF2C exerts an oncogenic role in nonsmall cell lung cancer and is negatively regulated by miR‐325‐3p
H Gan, L Lin, N Hu, Y Yang, Y Gao… - Cell biochemistry …, 2019 - Wiley Online Library
Nonsmall cell lung cancer (NSCLC) is one of the leading causes of cancer‐related death
worldwide. Kinesin family member 2C (KIF2C), a modulator in microtubule …
worldwide. Kinesin family member 2C (KIF2C), a modulator in microtubule …
[HTML][HTML] Comprehensive analysis of the effects of KIF2C on prognosis, biological functions and immune infiltration in PAAD
J Xiong, R Wu, A He, P Hou, J Wang, R Zhang, W Liao… - Tissue and Cell, 2022 - Elsevier
Kinesin family member 2 C (KIF2C), a modulator of microtubule depolymerization, bipolar
spindle formation, and chromosome segregation, has been reported to play roles in cancer …
spindle formation, and chromosome segregation, has been reported to play roles in cancer …