Superoxide dismutase 2 (SOD2) in vascular calcification: a focus on vascular smooth muscle cells, calcification pathogenesis, and therapeutic strategies

YT Tsai, HY Yeh, CT Chao… - Oxidative Medicine and …, 2021 - Wiley Online Library
Vascular calcification (VC) describes the pathophysiological phenotype of calcium apatite
deposition within the vascular wall, leading to vascular stiffening and the loss of compliance …

Oxidative stress in vascular calcification

CT Hu, YD Shao, YZ Liu, X Xiao, ZB Cheng, SL Qu… - Clinica chimica acta, 2021 - Elsevier
Vascular calcification (VC), which is closely associated with significant mortality in
cardiovascular disease, chronic kidney disease (CKD), and/or diabetes mellitus, is …

Vascular calcification—new insights into its mechanism

SJ Lee, IK Lee, JH Jeon - International journal of molecular sciences, 2020 - mdpi.com
Vascular calcification (VC), which is categorized by intimal and medial calcification,
depending on the site (s) involved within the vessel, is closely related to cardiovascular …

The role of mitochondria in vascular calcification

P Wang, N Zhang, B Wu, S Wu, Y Zhang… - Journal of Translational …, 2020 - degruyter.com
Vascular calcification (VC) was defined as the ectopic deposition of calcium–phosphorus
complexes on the blood vessel walls. It was a process involving multiple factors and …

Insights into the role of mitochondria in vascular calcification

ZL Zeng, Q Yuan, X Zu, J Liu - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
Vascular calcification (VC) is a growing burden in aging societies worldwide, and with a
significant increase in all-cause mortality and atherosclerotic plaque rupture, it is frequently …

Role of smooth muscle cells in vascular calcification: implications in atherosclerosis and arterial stiffness

AL Durham, MY Speer, M Scatena… - Cardiovascular …, 2018 - academic.oup.com
Vascular calcification is associated with a significant increase in all-cause mortality and
atherosclerotic plaque rupture. Calcification has been determined to be an active process …

Mitochondria homeostasis and vascular medial calcification

M Li, Y Zhu, SK Jaiswal, NF Liu - Calcified Tissue International, 2021 - Springer
Vascular calcification occurs highly prevalent, which commonly predicts adverse
cardiovascular events. The pathogenesis of calcification, a complicated and multifactorial …

Phenotypic plasticity of vascular smooth muscle cells in vascular calcification: Role of mitochondria

YZ Liu, ZX Li, LL Zhang, D Wang… - Frontiers in Cardiovascular …, 2022 - frontiersin.org
Vascular calcification (VC) is an important hallmark of cardiovascular disease, the osteo-
/chondrocyte phenotype differentiation of vascular smooth muscle cells (VSMCs) is the main …

Vascular calcification: Molecular mechanisms and therapeutic interventions

W Pan, W Jie, H Huang - MedComm, 2023 - Wiley Online Library
Vascular calcification (VC) is recognized as a pathological vascular disorder associated with
various diseases, such as atherosclerosis, hypertension, aortic valve stenosis, coronary …

Regulation of vascular calcification by reactive oxygen species

A Tóth, E Balogh, V Jeney - Antioxidants, 2020 - mdpi.com
Vascular calcification is the deposition of hydroxyapatite crystals in the medial or intimal
layers of arteries that is usually associated with other pathological conditions including but …