Influenza viruses constitute a major health threat and economic burden globally, frequently
exacerbated by preexisting or rapidly emerging resistance to antiviral therapeutics. To …

Seasonal influenza viruses cause major morbidity and mortality worldwide, threatening in
particular older adults and the immunocompromised. Two classes of influenza therapeutics …

Flu is caused by influenza viruses. The primary defense against influenza A and B is through
vaccination. Seasonal flu viruses constantly undergo antigenic variations by changing their …

Influenza viruses are a major threat to human health globally. In addition to further improving
vaccine prophylaxis, disease management through antiviral therapeutics constitutes an …

The emergence of the 2009 H1N1 pandemic influenza A virus, as well as constant antigenic
drift of seasonal influenza, underscores the remarkable versatility of this virus in adapting to …

Morbidity and mortality resulting from influenza-like disease are a threat, especially for older
adults. To improve case management, next-generation broad-spectrum antiviral …

Background: Influenza viruses cause severe upper respiratory illness in children and the
elderly during seasonal epidemics. Influenza viruses from zoonotic reservoirs can also …

Influenza has a long history of causing morbidity and mortality in the human population
through routine seasonal spread and global pandemics. The high mutation rate of the RNA …

Influenza is a global health concern, causing death, morbidity, and economic losses.
Chemotherapeutics that target influenza virus are available; however, rapid emergence of …

Emergence and re-emergence of respiratory virus infections represent a significant threat to
global public health, as they occur seasonally and less frequently (such as in the case of …