[HTML][HTML] Eslicarbazepine acetate: a new improvement on a classic drug family for the treatment of partial-onset seizures

GL Galiana, AC Gauthier, RH Mattson - Drugs in R&D, 2017 - Springer
Eslicarbazepine acetate is a new anti-epileptic drug belonging to the dibenzazepine
carboxamide family that is currently approved as adjunctive therapy and monotherapy for …

Eslicarbazepine acetate: an update on efficacy and safety in epilepsy

A Verrotti, G Loiacono, A Rossi, G Zaccara - Epilepsy research, 2014 - Elsevier
Epilepsy is a common neurological disorder. Despite a broad range of commonly used
antiepileptic drugs, approximately 30% of patients with epilepsy have drug resistance or …

A review of eslicarbazepine acetate for the adjunctive treatment of partial-onset epilepsy

RP Singh, JJ Asconapé - Journal of central nervous system …, 2011 - journals.sagepub.com
Eslicarbazepine acetate (ESL) is a novel antiepileptic drug indicated for the treatment of
partial-onset seizures. Structurally, it belongs to the dibenzazepine family and is closely …

Eslicarbazepine acetate: a review of its use as adjunctive therapy in refractory partial-onset seizures

GM Keating - CNS drugs, 2014 - Springer
Abstract Eslicarbazepine acetate (Aptiom®, Zebinix®) is approved for the adjunctive
treatment of partial-onset seizures in adults aged≥ 18 years. Adjunctive therapy with oral …

Role of eslicarbazepine in the treatment of epilepsy in adult patients with partial-onset seizures

ME Brown, RS El-Mallakh - Therapeutics and clinical risk …, 2010 - Taylor & Francis
Eslicarbazepine is a new dibenzazepine antiepileptic agent. It is a high affinity antagonist of
the voltage-gated sodium channel. It is closely related to both carbamazepine and …

A review of the efficacy and safety of eslicarbazepine acetate in the management of partial-onset seizures

R Rocamora - Therapeutic advances in neurological …, 2015 - journals.sagepub.com
Eslicarbazepine acetate is a is a once-daily antiepileptic drug (AED) that was approved in
2009 by the European Medicines Agency (EMA)(Zebinix™), and in 2013 by the US Food …

Long‐term efficacy and safety of eslicarbazepine acetate: results of a 1‐year open‐label extension study in partial‐onset seizures in adults with epilepsy

P Halász, JA Cramer, D Hodoba, A Członkowska… - …, 2010 - Wiley Online Library
Purpose: To evaluate the long‐term efficacy and safety of once daily eslicarbazepine
acetate (ESL) as adjunctive therapy for partial‐onset seizures in adults with epilepsy …

Eslicarbazepine acetate: a new option for the treatment of focal epilepsy

J Ferreira, T Mestre - Expert opinion on investigational drugs, 2009 - Taylor & Francis
Background: Epilepsy is a neurological condition with an increased probability of seizure
occurrence through time. Although many anti-epileptic drugs (AEDs) exist, they fail to treat …

[HTML][HTML] Eslicarbazepine acetate: its effectiveness as adjunctive therapy in clinical trials and open studies

SD Shorvon, E Trinka, BJ Steinhoff, M Holtkamp… - Journal of …, 2017 - Springer
Eslicarbazepine acetate (ESL) is a once-daily antiepileptic drug that is approved as
adjunctive therapy in adults with focal-onset seizures. Following oral administration, ESL is …

Eslicarbazepine acetate: a double‐blind, add‐on, placebo‐controlled exploratory trial in adult patients with partial‐onset seizures

C Elger, M Bialer, JA Cramer, J Maia, L Almeida… - …, 2007 - Wiley Online Library
Objective: To explore the efficacy and safety of eslicarbazepine acetate (BIA 2‐093), a new
antiepileptic drug, as adjunctive therapy in adult patients with partial epilepsy. Methods: A …