Recent work suggests that diet affects brain metabolism thereby impacting cognitive
function. Our objective was to determine if a western diet altered brain metabolism …

The goal of this study was to identify the intrinsic links that explain the effect of a Western diet
(WD) on cognitive dysfunction. Specific pathogen-free, wild-type mice were fed either a …

Background: Evidence has revealed an association between familial hypercholesterolemia
and cognitive impairment. In this regard, a connection between cognitive deficits and …

C57Bl/6 mice were administered a high fat, Western diet (WD, 41% fat) or a very high fat lard
diet (HFL, 60% fat), and evaluated for cognitive ability using the Stone T-maze and for …

Background/objectives The aim of the current study was to investigate the inhibitory effect of
lycopene (LYC), a major carotenoid present in tomato, on high-fat and high-fructose western …

Diabetes causes endothelial dysfunction and increases the risk of vascular cognitive
impairment. However, it is unknown whether diabetes causes cognitive impairment due to …

Lipid metabolism and genetic background together strongly influence the development of
both cardiovascular and neurodegenerative diseases like Alzheimer's disease (AD). A non …

High-fat diet (HFD) consumption is generally associated with an increased risk of cognitive
and emotional dysfunctions that constitute a sizeable worldwide health burden with …

Background: While vascular risk factors including Western-styled diet and obesity are
reported to induce cognitive decline and increase dementia risk, recent reports consistently …

Obesity in the western world has reached epidemic proportions, and yet the long-term
effects on brain health are not well understood. To address this, we performed …