Endothelial cell (EC) CD36 controls tissue fatty acid (FA) uptake. Here we examine how ECs
transfer FAs. FA interaction with apical membrane CD36 induces Src phosphorylation of …

Movement of circulating fatty acids (FAs) to parenchymal cells requires their transfer across
the endothelial cell (EC) barrier. The multiligand receptor cluster of differentiation 36 (CD36) …

CD36 is a multifunctional protein that enhances cellular fatty acid (FA) uptake, a key step in
energy metabolism, and its dysregulation in multiple tissue sites is central to obesity-linked …

Fatty acids (FAs) are essential nutrients, but how they are transported into cells remains
unclear. Here, we show that FAs trigger caveolae-dependent CD36 internalization, which in …

Membrane uptake of long-chain fatty acids (FAs) is the first step in cellular FA utilization and
a point of metabolic regulation. CD36 facilitates a major fraction of FA uptake by key tissues …

FAT/CD36 is a transmembrane protein that is thought to facilitate cellular long-chain fatty
acid uptake. However, surprisingly little is known about the localization of FAT/CD36 in …

The mechanism controlling long-chain fatty acid (LCFA) mobilization from adipose tissue is
not well understood. Here, we investigated how the LCFA transporter CD36 regulates this …

OBJECTIVE The fatty acid translocase and scavenger receptor CD36 is important in the
recognition and uptake of lipids. Accordingly, we hypothesized that it plays a role in …

Several lines of evidence suggest that lipid rafts are involved in cellular fatty acid uptake and
influence fatty acid translocase (FAT/CD36) function. However, it remains unknown whether …

Increasing evidence has implicated the membrane protein CD36 (FAT) in binding and
transport of long chain fatty acids (FA). To determine the physiological role of CD36, we …