1,25(OH)2D3 attenuates sleep disturbance in mouse models of Lewis lung cancer, in silico and in vivo
M Ai, S Li, H Chen, X Wang, J Sun… - Journal of Cellular …, 2021 - Wiley Online Library
Many clinical studies have reported that patients diagnosed with cancer will suffer from
sleep disturbance during their clinical process, especially among lung cancer patients, and …
sleep disturbance during their clinical process, especially among lung cancer patients, and …
[HTML][HTML] 1, 25 (OH) 2D3 mitigate cancer-related fatigue in tumor-bearing mice: Integrating network pharmacological analysis
Y Zhou, S Li, M Ai, H Chen, Y Liu, B Li, Y Zhao… - Biomedicine & …, 2020 - Elsevier
Cancer-related fatigue (CRF) is one of the most common and serious complications in
cancer patients, which greatly reduces the quality of life. The mechanism induced fatigue …
cancer patients, which greatly reduces the quality of life. The mechanism induced fatigue …
[HTML][HTML] Intermittent hypoxia enhances the tumor programmed death ligand 1 expression in a mouse model of sleep apnea
MH Huang, XB Zhang, HL Wang, LX Li… - Annals of …, 2019 - ncbi.nlm.nih.gov
Background As a hallmark of obstructive sleep apnea (OSA), intermittent hypoxia (IH)
promotes tumor progress. The high expression of programmed death 1 and programmed …
promotes tumor progress. The high expression of programmed death 1 and programmed …
1, 25 (OH) 2D3 inhibits hepatocellular carcinoma development through reducing secretion of inflammatory cytokines from immunocytes
J Guo, Z Ma, Q Ma, Z Wu, P Fan, X Zhou… - Current medicinal …, 2013 - ingentaconnect.com
Epidemiological and clinical studies have indicated that low vitamin D activity is not only
associated with an increased cancer risk and a more aggressive tumor growth, but also …
associated with an increased cancer risk and a more aggressive tumor growth, but also …
ALKBH5-m6A-FOXM1 signaling axis promotes proliferation and invasion of lung adenocarcinoma cells under intermittent hypoxia
Y Chao, J Shang, W Ji - Biochemical and biophysical research …, 2020 - Elsevier
Obstructive sleep apnea (OSA) is closely associated with cancer progression and cancer-
related mortality. N6-methyladenosine (m 6 A) is involved in the process of intermittent …
related mortality. N6-methyladenosine (m 6 A) is involved in the process of intermittent …
1,25(OH)2D3 inhibits Lewis lung cancer cell migration via NHE1‐sensitive metabolic reprograming
H Chen, M Zhu, X Wang, M Ai, S Li, M Wan… - IUBMB …, 2024 - Wiley Online Library
High prevalence and metastasis rates are characteristics of lung cancer. Glycolysis provides
energy for the development and metastasis of cancer cells. The 1, 25‐dihydroxy vitamin D3 …
energy for the development and metastasis of cancer cells. The 1, 25‐dihydroxy vitamin D3 …
[HTML][HTML] P4HA1 as an unfavorable prognostic marker promotes cell migration and invasion of glioblastoma via inducing EMT process under hypoxia microenvironment
X Zhu, S Liu, X Yang, W Wang, W Shao… - American Journal of …, 2021 - ncbi.nlm.nih.gov
This study aims to explore the mechanism of glioblastoma multiforme (GBM) in hypoxia
through metabolomic and proteomic analysis. We showed that the migration and …
through metabolomic and proteomic analysis. We showed that the migration and …
[HTML][HTML] Intermittent Hypoxia Promotes TAM-Induced Glycolysis in Laryngeal Cancer Cells via Regulation of HK1 Expression through Activation of ZBTB10
M Yang, W Cai, Z Lin, A Tuohuti, X Chen - International Journal of …, 2023 - mdpi.com
Obstructive sleep apnea (OSA), characterized by intermittent hypoxia (IH), may increase the
risk of cancer development and a poor cancer prognosis. TAMs of the M2 phenotype …
risk of cancer development and a poor cancer prognosis. TAMs of the M2 phenotype …
[HTML][HTML] Biosystem analysis of the hypoxia inducible domain family member 2A: implications in cancer biology
The expression of HIGD2A is dependent on oxygen levels, glucose concentration, and cell
cycle progression. This gene encodes for protein HIG2A, found in mitochondria and the …
cycle progression. This gene encodes for protein HIG2A, found in mitochondria and the …
Integrated Screening of Effective Anti-Insomnia Fractions of Zhi-Zi-Hou-Po Decoction via Drosophila melanogaster and Network Pharmacology Analysis of the …
Y Sun, R Zhao, R Liu, T Li, S Ni, H Wu, Y Cao, Y Qu… - ACS …, 2021 - ACS Publications
Insomnia is an anabatic epidemiology, while the mechanism is extremely complicated; it
remains one of the major scientific challenges in life sciences. Because of the advantage of …
remains one of the major scientific challenges in life sciences. Because of the advantage of …