PRC1-independent binding and activity of RYBP on the KSHV genome during de novo infection
SC Lee, Z Toth - PLoS Pathogens, 2022 - journals.plos.org
Kaposi's sarcoma-associated herpesvirus (KSHV) is an oncogenic virus that causes lifelong
infection in humans by establishing latency after primary infection. Latent infection is a …
infection in humans by establishing latency after primary infection. Latent infection is a …
LANA-Mediated Recruitment of Host Polycomb Repressive Complexes onto the KSHV Genome during De Novo Infection
One of the hallmarks of the latent phase of Kaposi's sarcoma-associated herpesvirus
(KSHV) infection is the global repression of lytic viral gene expression. Following de novo …
(KSHV) infection is the global repression of lytic viral gene expression. Following de novo …
Kruppel-associated box domain-associated protein-1 as a latency regulator for Kaposi's sarcoma-associated herpesvirus and its modulation by the viral protein kinase
PC Chang, LD Fitzgerald, A Van Geelen, Y Izumiya… - Cancer research, 2009 - AACR
Kaposi's sarcoma-associated herpesvirus (KSHV) has been linked to the development of
Kaposi's sarcoma, a major AIDS-associated malignancy, and to hematologic malignancies …
Kaposi's sarcoma, a major AIDS-associated malignancy, and to hematologic malignancies …
Epigenetic factor siRNA screen during primary KSHV infection identifies novel host restriction factors for the lytic cycle of KSHV
NG Naik, TH Nguyen, L Roberts, LT Fischer… - PLoS …, 2020 - journals.plos.org
Establishment of viral latency is not only essential for lifelong Kaposi's sarcoma-associated
herpesvirus (KSHV) infection, but it is also a prerequisite of viral tumorigenesis. The latent …
herpesvirus (KSHV) infection, but it is also a prerequisite of viral tumorigenesis. The latent …
A comparative epigenome analysis of gammaherpesviruses suggests cis-acting sequence features as critical mediators of rapid polycomb recruitment
T Günther, J Fröhlich, C Herrde, S Ohno… - PLoS …, 2019 - journals.plos.org
Latent Kaposi sarcoma-associated herpesvirus (KSHV) genomes rapidly acquire distinct
patterns of the activating histone modification H3K4-me3 as well as repressive H3K27-me3 …
patterns of the activating histone modification H3K4-me3 as well as repressive H3K27-me3 …
Chromatin remodeling controls Kaposi's sarcoma-associated herpesvirus reactivation from latency
Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiologic agent of three human
malignancies, the endothelial cell cancer Kaposi's sarcoma, and two B cell cancers, Primary …
malignancies, the endothelial cell cancer Kaposi's sarcoma, and two B cell cancers, Primary …
The transcriptional repressor K-RBP modulates RTA-mediated transactivation and lytic replication of Kaposi's sarcoma-associated herpesvirus
The replication and transcription activator (RTA) protein of Kaposi's sarcoma (KS)-
associated herpesvirus (KSHV)/human herpesvirus 8 functions as the key regulator to …
associated herpesvirus (KSHV)/human herpesvirus 8 functions as the key regulator to …
Screening of the human kinome identifies MSK1/2-CREB1 as an essential pathway mediating Kaposi's sarcoma-associated herpesvirus lytic replication during …
F Cheng, TV Sawant, K Lan, C Lu, JU Jung… - Journal of …, 2015 - Am Soc Microbiol
Viruses often hijack cellular pathways to facilitate infection and replication. Kaposi's sarcoma-
associated herpesvirus (KSHV) is an oncogenic gammaherpesvirus etiologically associated …
associated herpesvirus (KSHV) is an oncogenic gammaherpesvirus etiologically associated …
Inhibition of KAP1 enhances hypoxia-induced Kaposi's sarcoma-associated herpesvirus reactivation through RBP-Jκ
Hypoxia-inducible factor 1α (HIF-1α) has been frequently implicated in many cancers as well
as viral pathogenesis. Kaposi's sarcoma-associated herpesvirus (KSHV) is linked to several …
as viral pathogenesis. Kaposi's sarcoma-associated herpesvirus (KSHV) is linked to several …
KSHV lytic proteins K-RTA and K8 bind to cellular and viral chromatin to modulate gene expression
The oncogenic Kaposi's sarcoma-associated herpesvirus (KSHV) has two distinct life cycles
with lifelong latent/non-productive and a sporadic lytic-reactivating/productive phases in the …
with lifelong latent/non-productive and a sporadic lytic-reactivating/productive phases in the …