Compelling data demonstrate that inflammation-associated anorexia directly results from the
action of pro-inflammatory factors, primarily cytokines and prostaglandins E2, on the nervous …

The anorexia-cachexia syndrome is a debilitating clinical condition characterizing the
course of chronic diseases, which heavily impacts on patients' morbidity and quality of life …

Our research focuses on the mechanisms underlying cytokine action in the central nervous
system (CNS) using an integrative and multidisciplinary strategy organized through …

Decreased appetite and involuntary weight loss are common occurrences in chronic
disease and have a negative impact on both quality of life and eventual mortality. Weight …

Data from both rodent models and humans suggest that intact neuronal melanocortin
signaling is essential to prevent obesity, as mutations that decrease the melanocortin signal …

The cachexia–anorexia syndrome occurs in chronic pathophysiologic processes including
cancer, infection with human immunodeficiency virus, bacterial and parasitic diseases …

Under normal conditions, the homeostasis of energy intake is maintained in the
hypothalamus by 1) transducing metabolic and sensorial inputs arising from the periphery …

The anorexia of infection is part of the host's acute phase response (APR). Despite being
beneficial in the beginning, long lasting anorexia delays recovery and is ultimately …

Given the high‐energy requirements to sustain immune responses and healing processes, it
is intriguing that lack of appetite (ie, anorexia) is a cardinal feature of sickness behaviour …

Anorexia and involuntary weight loss are common and debilitating complications of a
number of chronic diseases and inflammatory states. Proinflammatory cytokines, including IL …