The nuclear erythroid 2-related factor 2 (Nrf2) signaling pathway has a main role against
oxidative stress and inflammation. Spinal Cord Injury (SCI) leads to the high secretion of …

Nuclear factor erythroid-2-related factor 2 (Nrf2) is a pleiotropic transcription factor, and it
has been documented that it can induce defense mechanisms both oxidative stress and …

Spinal cord injury (SCI) is a central nervous system trauma that can cause severe
neurological impairment. A series of pathological and physiological changes after SCI (eg …

The nuclear erythroid 2-related factor 2 (Nrf2)/antioxidant response element (ARE) signaling
pathway plays an essential role in the cellular antioxidant and anti-inflammatory responses …

BACKGROUND: Inflammation plays an important role in the pathogenesis of secondary
damage after spinal cord injury (SCI). Previous studies have suggested that nuclear factor …

Matrix metalloproteinase‐9 (MMP‐9) plays an important role in the acute periods of spinal
cord injury (SCI), and its expression is related to the inflammation which could cause the …

In the dynamic landscape of neuroscience and regenerative medicine, the pivotal role of
neuroglia, or glial cells, is increasingly being recognized. These cells, historically deemed …

Background Spinal cord injury (SCI) induces a multitude of deleterious processes, including
neuroinflammation and oxidative stress (OS) which contributed to neuronal damage and …

Central nervous system (CNS) trauma, such as traumatic brain injury (TBI) and spinal cord
injury (SCI), represents an increasingly important health burden in view of the preventability …

As an essential component of cellular defense against a variety of endogenous and
exogenous stresses, nuclear factor erythroid 2-related factor 2 (Nrf2) has received increased …