While most tissues exhibit their greatest growth during development, adipose tissue is
capable of additional massive expansion in adults. Adipose tissue expandability is …

The growth and function of tissues are critically dependent on their vascularization. Adipose
tissue is capable of expanding many-fold during adulthood, therefore requiring the formation …

Obesity is a common disorder and related diseases, such as diabetes, atherosclerosis,
hypertension, cardiovascular disease and cancer, are a major cause of mortality and …

Obesity is a worldwide health problem, and as its prevalence increases, so does the burden
of obesity-associated co-morbidities like type 2 diabetes or cardiovascular diseases (CVDs) …

OBJECTIVE—The expansion of adipose tissue mass seen in obesity involves both
hyperplasia and hypertrophy of adipocytes. However, little is known about how adipocytes …

White and brown adipose tissues are hypervascularized and the adipose vasculature
displays phenotypic and functional plasticity to coordinate with metabolic demands of …

Adipose tissue is the most plastic tissue in all multicellular organisms, being constantly
remodelled along with weight gain and weight loss. Expansion of adipose tissue must be …

Adipose tissue expansion involves the enlargement of existing adipocytes, the formation of
new cells from committed preadipocytes, and the coordinated development of the tissue …

With an increasing incidence of obesity worldwide, rational strategies are needed to control
adipogenesis. Growth of any tissue requires the formation of a functional and mature …

Genetic and diet-induced rodent obesity models provide outstanding opportunities to study
the role of angiogenesis and vascular remodeling in modulation of adipogenesis and …