Virus mechanics under molecular crowding
Viruses avoid exposure of the viral genome to harmful agents with the help of a protective
protein shell known as the capsid. A secondary effect of this protective barrier is that …
protein shell known as the capsid. A secondary effect of this protective barrier is that …
Relevance of capsid structure in the buckling and maturation of spherical viruses
The shape and mechanical properties of viral capsids play an important role in several
biological processes during the virus life cycle. In particular, to become infective, many …
biological processes during the virus life cycle. In particular, to become infective, many …
The effect of RNA stiffness on the self-assembly of virus particles
S Li, G Erdemci-Tandogan… - Journal of Physics …, 2017 - iopscience.iop.org
Under many in vitro conditions, some small viruses spontaneously encapsidate a single
stranded (ss) RNA into a protein shell called the capsid. While viral RNAs are found to be …
stranded (ss) RNA into a protein shell called the capsid. While viral RNAs are found to be …
Intermittency of deformation and the elastic limit of an icosahedral virus under compression
Viruses undergo mesoscopic morphological changes as they interact with host interfaces
and in response to chemical cues. The dynamics of these changes, over the entire temporal …
and in response to chemical cues. The dynamics of these changes, over the entire temporal …
Mechanical deformation of spherical viruses with icosahedral symmetry
GA Vliegenthart, G Gompper - Biophysical journal, 2006 - cell.com
Virus capsids and crystalline surfactant vesicles are two examples of self-assembled shells
in the nano-to micrometer size range. Virus capsids are particularly interesting since they …
in the nano-to micrometer size range. Virus capsids are particularly interesting since they …
Structure and energetics guide dynamic behaviour in a T= 3 icosahedral virus capsid
G Shrivastav, S Borkotoky, D Dey, B Singh… - Biophysical …, 2024 - Elsevier
Although virus capsids appear as rigid, symmetric particles in experimentally determined
structures; biochemical studies suggest a significant degree of structural flexibility in the …
structures; biochemical studies suggest a significant degree of structural flexibility in the …
How a virus circumvents energy barriers to form symmetric shells
Previous self-assembly experiments on a model icosahedral plant virus have shown that,
under physiological conditions, capsid proteins initially bind to the genome through an en …
under physiological conditions, capsid proteins initially bind to the genome through an en …
Entropic control of particle sizes during viral self-assembly
M Castelnovo, D Muriaux… - New Journal of …, 2013 - iopscience.iop.org
Morphologic diversity is observed across all families of viruses. However, these supra-
molecular assemblies are produced most of the time in a spontaneous way through complex …
molecular assemblies are produced most of the time in a spontaneous way through complex …
Mechanical properties of viral capsids
Viruses are known to tolerate wide ranges of p H and salt conditions and to withstand
internal pressures as high as 100 atmospheres. In this paper we investigate the mechanical …
internal pressures as high as 100 atmospheres. In this paper we investigate the mechanical …
Virus assembly pathways inside a host cell
Simple RNA viruses self-assemble spontaneously and encapsulate their genome into a
shell called the capsid. This process is mainly driven by the attractive electrostatics …
shell called the capsid. This process is mainly driven by the attractive electrostatics …