Conservative analysis of Synaptopodin‐2 intron sense‐overlapping lncRNA reveals its novel function in promoting muscle atrophy

J Jin, M Du, J Wang, Y Guo, J Zhang… - Journal of cachexia …, 2022 - Wiley Online Library
Background Dissection of the regulatory pathways that control skeletal muscle development
and atrophy is important for the treatment of muscle wasting. Long noncoding RNA (lncRNA) …

Long noncoding RNA SYISL regulates myogenesis by interacting with polycomb repressive complex 2

JJ Jin, W Lv, P Xia, ZY Xu, AD Zheng… - Proceedings of the …, 2018 - National Acad Sciences
Although many long noncoding RNAs (lncRNAs) have been identified in muscle, their
physiological function and regulatory mechanisms remain largely unexplored. In this study …

LncIRS1 controls muscle atrophy via sponging miR‐15 family to activate IGF1‐PI3K/AKT pathway

Z Li, B Cai, BA Abdalla, X Zhu, M Zheng… - Journal of cachexia …, 2019 - Wiley Online Library
Background Recent studies indicate important roles for long noncoding RNAs (lncRNAs) in
the regulation of gene expression by acting as competing endogenous RNAs (ceRNAs) …

[HTML][HTML] LncEDCH1 improves mitochondrial function to reduce muscle atrophy by interacting with SERCA2

B Cai, M Ma, J Zhang, Z Wang, S Kong, Z Zhou… - … Therapy-Nucleic Acids, 2022 - cell.com
Skeletal muscle is a regulator of the body's energy expenditure and metabolism. Abnormal
regulation of skeletal muscle-specific genes leads to various muscle diseases. Long non …

[HTML][HTML] An analysis of differentially expressed coding and long non-coding RNAs in multiple models of skeletal muscle atrophy

K Hitachi, M Nakatani, Y Kiyofuji, H Inagaki… - International journal of …, 2021 - mdpi.com
The loss of skeletal muscle mass (muscle atrophy or wasting) caused by aging, diseases,
and injury decreases quality of life, survival rates, and healthy life expectancy in humans …

Long noncoding RNA lncMREF promotes myogenic differentiation and muscle regeneration by interacting with the Smarca5/p300 complex

W Lv, W Jiang, H Luo, Q Tong, X Niu, X Liu… - Nucleic Acids …, 2022 - academic.oup.com
Long noncoding RNAs (lncRNAs) play important roles in the spatial and temporal regulation
of muscle development and regeneration. Nevertheless, the determination of their biological …

[HTML][HTML] The functional role of long non-coding RNA in myogenesis and skeletal muscle atrophy

K Hitachi, M Honda, K Tsuchida - Cells, 2022 - mdpi.com
Skeletal muscle is a pivotal organ in humans that maintains locomotion and homeostasis.
Muscle atrophy caused by sarcopenia and cachexia, which results in reduced muscle mass …

[HTML][HTML] LncRNA SMARCD3-OT1 Promotes Muscle Hypertrophy and Fast-Twitch Fiber Transformation via Enhancing SMARCD3X4 Expression

J Zhang, B Cai, M Ma, S Kong, Z Zhou… - International Journal of …, 2022 - mdpi.com
Long noncoding RNA (lncRNA) plays a crucial part in all kinds of life activities, especially in
myogenesis. SMARCD3 (SWI/SNF-related, matrix-associated, actin-dependent regulator of …

A newly identified lncRNA MAR1 acts as a miR‐487b sponge to promote skeletal muscle differentiation and regeneration

ZK Zhang, J Li, D Guan, C Liang, Z Zhuo… - Journal of cachexia …, 2018 - Wiley Online Library
Background Skeletal muscle atrophy induced by either aging (sarcopenia) or mechanical
unloading is associated with serious health consequences. Long non‐coding RNAs …

[HTML][HTML] Expression levels of long non-coding RNAs change in models of altered muscle activity and muscle mass

K Hitachi, M Nakatani, S Funasaki, I Hijikata… - International journal of …, 2020 - mdpi.com
Skeletal muscle is a highly plastic organ that is necessary for homeostasis and health of the
human body. The size of skeletal muscle changes in response to intrinsic and extrinsic …