Neurodegenerative diseases (NDs) are a diverse group of disorders characterized by the
progressive degeneration and death of neurons, leading to a range of neurological …

Mitochondria play a central role in a plethora of processes related to the maintenance of
cellular homeostasis and genomic integrity. They contribute to preserving the optimal …

Neurodegenerative diseases are incurable and devastating neurological disorders
characterized by the progressive loss of the structure and function of neurons in the central …

Research efforts during the last decade have deciphered the basic molecular mechanisms
governing mitochondrial fusion and fission. We now know that in mammalian cells …

Mitochondria are highly dynamic organelles, which undergo frequent structural and
metabolic changes to fulfil cellular demands. To facilitate these processes several proteins …

Mitochondria are dynamic organelles that continually move, fuse and divide. The dynamic
balance of fusion and fission of mitochondria determines their morphology and allows their …

Mitochondria are key organelles in eukaryotic cells that not only generate adenosine
triphosphate but also perform such critical functions as hosting essential biosynthetic …

Mitochondrial dysfunction is increasingly being recognized as an important factor
contributing to the pathogenesis of neurodegenerative disorders. However, at present, the …

Neurodegenerative diseases are incurable and inexorably progressive conditions that affect
the central nervous system and result in a selective pattern of neuronal death. Parkinson's …

Mitochondria are important cellular organelles in most metabolic processes and have a
highly dynamic nature, undergoing frequent fission and fusion. The dynamic balance …