AIMS: To investigate the in vivo effect of glucosamine on articular cartilage in osteoarthritis
(OA), we evaluated serum biomarkers such as CTX-II (type II collagen degradation) and CPII …

Objective To determine whether oral glucosamine alleviates cartilage degradation in an
animal model of osteoarthritis (OA). Methods The effect of 8 weeks of daily oral glucosamine …

Abstract Background Glucosamine (GlcN) is a well-recognized candidate for treatment of
osteoarthritis. However, it is currently used in derivative forms, such as glucosamine …

The aim of this pilot study was to analyze the effects of glucosamine (GlcN) and its N-acetyl-
phenylalanine derivative (NAPA) in Vitamin A model of osteoarthritis (OA) in rabbits. GlcN or …

It has been demonstrated that oral administration of N-acetylglucosamine (GlcNAc)
alleviates the symptoms of osteoarthritis (OA). The aim of the present study was to elucidate …

Objective Osteoarthritis (OA) is a complex disease of the whole joint. Glucosamine (GlcN)
treatment may have a chondroprotective effect on OA. We investigated the mechanism of …

Introduction Glucosamine is an amino-monosaccharide and precursor of
glycosaminoglycans, major components of joint cartilage. Glucosamine has been clinically …

Glucosamine (GlcN) has been widely used to treat osteoarthritis (OA) in humans. However,
its chondroprotective action on the joint is poorly understood. In this study, to elucidate the …

N-acetylglucosamine (GlcNAc) is a widely accepted treatment for osteoarthritis (OA);
however, its effect on healthy individuals is poorly understood. To evaluate the effect of …

Glucosamine (GlcN) has been widely used to treat osteoarthritis (OA) in humans. We
revealed that among GlcN-derivatives (GlcN and N-acetyl-d-glucosamine) and uronic acids …