Transdermal delivery allows continuous systemic application of opioids through the intact
skin. This review analyses the pharmacokinetic properties of transdermal opioid …

Fentanyl is a synthetic opioid with short-acting analgesic activity after intravenous or
subcutaneous administration. The low molecular weight, high potency and lipid solubility of …

The transdermal route of drug delivery has been used for the effective administration of
therapeutic agents for more than a decade. The most important consideration in selecting a …

Fentanyl is a synthetic opioid agonist which interacts primarily with the μ-opioid receptor.
The low molecular weight, high potency and lipid solubility of fentanyl make it suitable for …

Background The transdermal therapeutic system (fentanyl), or TTS (fentanyl), continuously
delivers fentanyl for up to 72 h. The transdermal therapeutic system (fentanyl)-100 delivers …

Transdermal (TTS) fentanyl therapy has emerged as an effective alternative to the use of
oral opioids for the control of pain in certain cancer patients. These patients are those with …

The transdermal therapeutic system (TTS) fentanyl has been designed for rate-controlled
drug delivery. It provides a convenient regimen for the use of a drug previously limited by a …

Fentanyl has been incorporated into a transdermal therapeutic system (TTS) containing a
rate-limiting membrane that provides constant release of the opioid. TTS fentanyl provides …

Transdermal fentanyl is effective and well tolerated for the treatment of chronic pain caused
by malignancy and non-malignant conditions when administered according to the …

A new transdermal drug‐delivery system that administers the synthetic opioid fentanyl
through intact skin was evaluated for 24 hours postoperatively in eight patients who had …