[HTML][HTML] Human regulatory T cells: understanding the role of tregs in select autoimmune skin diseases and post-transplant nonmelanoma skin cancers
NC Oparaugo, K Ouyang, NPN Nguyen… - International journal of …, 2023 - mdpi.com
Regulatory T cells (Tregs) play an important role in maintaining immune tolerance and
homeostasis by modulating how the immune system is activated. Several studies have …
homeostasis by modulating how the immune system is activated. Several studies have …
[HTML][HTML] The therapeutic potential of regulatory T cells: challenges and opportunities
F Bayati, M Mohammadi, M Valadi, S Jamshidi… - Frontiers in …, 2021 - frontiersin.org
Regulatory T cells (Tregs) are an immunosuppressive subgroup of CD4+ T cells which are
identified by the expression of forkhead box protein P3 (Foxp3). The modulation capacity of …
identified by the expression of forkhead box protein P3 (Foxp3). The modulation capacity of …
Therapeutic opportunities for manipulating TReg cells in autoimmunity and cancer
H Von Boehmer, C Daniel - Nature reviews Drug discovery, 2013 - nature.com
Abstract Forkhead box P3 (FOXP3)-expressing regulatory T (TReg) cells have a pivotal role
in the regulation of immune responses and in the maintenance of immunological self …
in the regulation of immune responses and in the maintenance of immunological self …
Regulatory T cells: molecular and cellular basis for immunoregulation
Y Togashi, H Nishikawa - … Targeting Immune Checkpoints in Cancer and …, 2017 - Springer
CD4+ regulatory T cells (Tregs) are a highly immune-suppressive subset of CD4+ T cells,
characterized by expression of the master regulatory transcription factor FOXP3. Tregs are …
characterized by expression of the master regulatory transcription factor FOXP3. Tregs are …
[HTML][HTML] Regulatory T cells in autoimmunity and cancer: a duplicitous lifestyle
A Hatzioannou, A Boumpas, M Papadopoulou… - Frontiers in …, 2021 - frontiersin.org
Regulatory T (Treg) cells, possess a strategic role in the maintenance of immune
homeostasis, and their function has been closely linked to development of diverse …
homeostasis, and their function has been closely linked to development of diverse …
Different subpopulations of regulatory T cells in human autoimmune disease, transplantation, and tumor immunity
Z Jiang, H Zhu, P Wang, W Que, L Zhong, XK Li… - MedComm, 2022 - Wiley Online Library
Abstract CD4+ CD25+ regulatory T cells (Tregs), a subpopulation of naturally CD4+ T cells
that characteristically express transcription factor Forkhead box P3 (FOXP3), play a pivotal …
that characteristically express transcription factor Forkhead box P3 (FOXP3), play a pivotal …
[HTML][HTML] Regulatory T cells: banned cells for decades
K Loser, S Beissert - Journal of investigative dermatology, 2012 - Elsevier
Regulatory T cells (Tregs), either thymic derived or peripherally induced, suppress a variety
of physiological and pathological immune responses, and the absence of this cell subset …
of physiological and pathological immune responses, and the absence of this cell subset …
Regulatory T cells as therapeutic targets and mediators
A Sharma, D Rudra - International Reviews of Immunology, 2019 - Taylor & Francis
With the advent of the concept of dominant tolerance and the subsequent discovery of CD4+
regulatory T cells expressing the transcription factor FOXP3 (Tregs), almost all productive as …
regulatory T cells expressing the transcription factor FOXP3 (Tregs), almost all productive as …
[HTML][HTML] Opportunities for Treg cell therapy for the treatment of human disease
JA Bluestone, BS McKenzie, J Beilke… - Frontiers in …, 2023 - frontiersin.org
Regulatory T (Treg) cells are essential for maintaining peripheral tolerance, preventing
autoimmunity, and limiting chronic inflammatory diseases. This small CD4+ T cell population …
autoimmunity, and limiting chronic inflammatory diseases. This small CD4+ T cell population …
CD4+ T‐regulatory cells: toward therapy for human diseases
SE Allan, R Broady, S Gregori, ME Himmel… - Immunological …, 2008 - Wiley Online Library
T‐regulatory cells (Tregs) have a fundamental role in the establishment and maintenance of
peripheral tolerance. There is now compelling evidence that deficits in the numbers and/or …
peripheral tolerance. There is now compelling evidence that deficits in the numbers and/or …
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