Screening of ToxCast chemicals responsible for human adverse outcomes with exposure to ambient air
L Qiao, L Gao, D Huang, Y Liu, C Xu, D Li… - … Science & Technology, 2022 - ACS Publications
Air pollution poses a major threat to global public health. Although there have been a few
investigations into the relationships between organic pollutants and adverse outcomes, the …
investigations into the relationships between organic pollutants and adverse outcomes, the …
A toxicogenomic comparison of primary and photochemically altered air pollutant mixtures
JE Rager, K Lichtveld, S Ebersviller… - Environmental …, 2011 - ehp.niehs.nih.gov
Background: Air pollution contributes significantly to global increases in mortality,
particularly within urban environments. Limited knowledge exists on the mechanisms …
particularly within urban environments. Limited knowledge exists on the mechanisms …
Human indoor exposome of chemicals in dust and risk prioritization using EPA's ToxCast database
Humans spend most of their time indoors and thus have long-term exposure to chemicals.
Dust is a sink for most indoor chemicals, and its ingestion is an important pathway for …
Dust is a sink for most indoor chemicals, and its ingestion is an important pathway for …
Improving the human hazard characterization of chemicals: a Tox21 update
RR Tice, CP Austin, RJ Kavlock… - Environmental health …, 2013 - ehp.niehs.nih.gov
Background: In 2008, the National Institute of Environmental Health Sciences/National
Toxicology Program, the US Environmental Protection Agency's National Center for …
Toxicology Program, the US Environmental Protection Agency's National Center for …
Exploring the occurrence and temporal variation of ToxCast chemicals in fine particulate matter using suspect screening strategy
Y Lin, J Yang, Q Fu, T Ruan… - Environmental science & …, 2019 - ACS Publications
Existence of emerging contaminants in the environment is of great importance for health risk
assessment. The consensus on categories and numbers of the emerging contaminants in …
assessment. The consensus on categories and numbers of the emerging contaminants in …
Leveraging the comparative toxicogenomics database to fill in knowledge gaps for environmental health: a test case for air pollution-induced cardiovascular disease
AP Davis, TC Wiegers, CJ Grondin… - Toxicological …, 2020 - academic.oup.com
Environmental health studies relate how exposures (eg, chemicals) affect human health and
disease; however, in most cases, the molecular and biological mechanisms connecting an …
disease; however, in most cases, the molecular and biological mechanisms connecting an …
[HTML][HTML] Exposure and toxicity characterization of chemical emissions and chemicals in products: global recommendations and implementation in USEtox
Purpose Reducing chemical pressure on human and environmental health is an integral
part of the global sustainability agenda. Guidelines for deriving globally applicable, life cycle …
part of the global sustainability agenda. Guidelines for deriving globally applicable, life cycle …
[HTML][HTML] Comment on “On the Utility of ToxCast™ and ToxPi as Methods for Identifying New Obesogens”
Janesick and colleagues recently published an evaluation of the utility of ToxCast™ and
Tox21 bioactivity data for predicting PPARγ activation and induction of adipogenesis. As …
Tox21 bioactivity data for predicting PPARγ activation and induction of adipogenesis. As …
[HTML][HTML] An annotation database for chemicals of emerging concern in exposome research
J Meijer, M Lamoree, T Hamers, JP Antignac… - Environment …, 2021 - Elsevier
Abstract Background Chemicals of Emerging Concern (CECs) include a very wide group of
chemicals that are suspected to be responsible for adverse effects on health, but for which …
chemicals that are suspected to be responsible for adverse effects on health, but for which …
The exposome and toxicology: a win–win collaboration
R Barouki, K Audouze, C Becker, L Blaha… - Toxicological …, 2022 - academic.oup.com
The development of the exposome concept has been one of the hallmarks of environmental
and health research for the last decade. The exposome encompasses the life course …
and health research for the last decade. The exposome encompasses the life course …