Genistein improves thyroid function in Hashimoto's thyroiditis patients through regulating Th1 cytokines

K Zhang, Y Wang, W Ma, Z Hu, P Zhao - Immunobiology, 2017 - Elsevier
Hashimoto thyroiditis (HT) is a common autoimmune disease. Genistein is an isoflavone
with immunomodulatory functions in various diseases. In this double-blind, randomized …

Anti-inflammatory effects of luteolin on experimental autoimmune thyroiditis in mice

N Xia, G Chen, M Liu, X Ye, Y Pan… - Experimental and …, 2016 - spandidos-publications.com
Hashimoto's thyroiditis (HT) is the most common organ‑specific autoimmune disease and is
believed to be a predominately T cell‑mediated autoimmunity. Signal transducer and …

Nigella Sativa treatment and serum concentrations of thyroid hormones, transforming growth factor β (TGF-β) and interleukin 23 (IL-23) in patients with Hashimoto's …

S Tajmiri, MA Farhangi, P Dehghan - European Journal of Integrative …, 2016 - Elsevier
Introduction Hashimoto's thyroiditis is an autoimmune disorder and is the most common
cause of hypothyroidism. The use of herbal medicine continues to increase worldwide as an …

Increased proportions of Tc17 cells and NK cells may be risk factors for disease progression in Hashimoto's thyroiditis

Y Liu, R You, N Yu, Y Gong, C Qu, Y Zhang… - International …, 2016 - Elsevier
Both cellular and humoral responses play important roles in the pathogenesis of
Hashimoto's thyroiditis (HT). However, the immunological differences between euthyroid …

Modulation of T-Bet and GATA-3 expression in experimental autoimmune thyroiditis rats through ginsenoside treatment

J Chen, X Feng, Q Huang - Endocrine Research, 2016 - Taylor & Francis
Hashimoto's thyroiditis (HT) is one of the most common organ-specific autoimmune
diseases. Increasing evidence indicates that HT may be characterized by an imbalance in …

Measurement of IL-12 and IL-18 in sera of patients with autoimmune thyroid disease

JA Zhang, J Zhang, L Xu, H Mar… - Xi bao yu fen zi Mian yi xue …, 2006 - europepmc.org
Aim To provide some evidence for the imbalance of Th1/Th2 cells in patients with
autoimmune thyroid disease (AITD). Methods Concentrations of IL-12 and IL-18 in the serum …

[HTML][HTML] Genistein inhibits human papillary thyroid cancer cell detachment, invasion and metastasis

C Zhang, B Lv, C Yi, X Cui, S Sui, X Li, M Qi… - Journal of …, 2019 - ncbi.nlm.nih.gov
Papillary thyroid carcinoma (PTC) is the most commonly diagnosed endocrine cancer, and
those with BRAF V600E mutation have high recurrence rate and less favorable clinical …

Genistein attenuated allergic airway inflammation by modulating the transcription factors T-bet, GATA-3 and STAT-6 in a murine model of asthma

F Gao, D Wei, T Bian, P Xie, J Zou, H Mu, B Zhang… - Pharmacology, 2012 - karger.com
Background: Genistein, a flavonoid in legumes and some herbal medicines, has various
biological actions. Previous studies have shown that genistein decreased airway …

Tripterygium wilfordii saponins and interleukin-10 prevent induction of experimental autoimmune thyroiditis by dendritic cells.

SJ Wang, HX Xu, GZ Liu - Acta Pharmacologica Sinica, 2000 - europepmc.org
Aim To study the roles of Tripterygium wilfordii saponins (TII) and interleukin-10 (IL-10) on
dendritic cells (DC)-induced experimental autoimmune thyroiditis (EAT). Methods We used …

[HTML][HTML] Effect of emodin on T cell subsets in NOD mice with NaI‑induced experimental autoimmune thyroiditis

H Sun, Z Ye, N Li, F Jin, J Yan… - Molecular Medicine …, 2018 - spandidos-publications.com
Chronic lymphocytic thyroiditis (CLT), also known as Hashimoto's thyroiditis, is an
autoimmune disease in which the thyroid gland is gradually destroyed. To date, only a …