Estrogen receptor gene analysis in estrogen receptor-positive and receptor-negative primary breast cancer
N Roodi, LR Bailey, WY Kao, CS Verrier… - JNCI: Journal of the …, 1995 - academic.oup.com
Background: In breast cancer patients, about two thirds of the tumors are estrogen receptor
(ER)-positive and one third are ER-negative. The molecular mechanisms leading to the ER …
(ER)-positive and one third are ER-negative. The molecular mechanisms leading to the ER …
Estrogen receptor variants in normal human mammary tissue
Background Several estrogen receptor (ER) variant messenger RNAs (mRNAs) have been
identified previously in human breast cancer biopsy samples and cell lines. The relative …
identified previously in human breast cancer biopsy samples and cell lines. The relative …
Expression of a constitutively active estrogen receptor variant in the estrogen receptor-negative BT-20 human breast cancer cell line
Estrogen receptor (ER) expression by breast tumors is an important predictor of disease-free
survival in breast cancer patients and, more importantly, is a strong predictor of response to …
survival in breast cancer patients and, more importantly, is a strong predictor of response to …
Estrogen receptor expression in human breast cancer associated with an estrogen receptor gene restriction fragment length polymorphism
Estrogen receptor (ER) content is a well-known predictor of clinical outcome in human
breast cancer. The recent cloning of a human ER complementary DNA has made possible …
breast cancer. The recent cloning of a human ER complementary DNA has made possible …
An exon 5 deletion variant of the estrogen receptor frequently coexpressed with wild-type estrogen receptor in human breast cancer
Recent evidence suggests that the expression of estrogen receptor (ER) variants in breast
cancer may interfere with wild-type (wt) ER function and be related to tumor progression and …
cancer may interfere with wild-type (wt) ER function and be related to tumor progression and …
Genomic DNA analysis of the estrogen receptor gene in breast cancer
FF Parl, DR Cavener, WD Dupont - Breast cancer research and treatment, 1989 - Springer
A human estrogen receptor (ER) cDNA probe was used to examine genomic DNA extracted
from 59 primary invasive breast cancers. The tumors were also studied histopathologically …
from 59 primary invasive breast cancers. The tumors were also studied histopathologically …
Transcriptional control of estrogen receptor in estrogen receptor-negative breast carcinoma
RJ Weigel, EC deConinck - Cancer research, 1993 - AACR
The mechanisms which control estrogen receptor (ER) expression in breast carcinoma have
not been elucidated. The MCF-7 (ER-positive) and MDA-MB-231 (ER-negative) breast …
not been elucidated. The MCF-7 (ER-positive) and MDA-MB-231 (ER-negative) breast …
Identification of a variant form of the human estrogen receptor with an amino acid replacement.
Estrogen receptor (ER) is a ligand-dependent transcriptional regulator. ER protein has
several functionally distinct regions, including a DNA-binding domain in its midportion, a …
several functionally distinct regions, including a DNA-binding domain in its midportion, a …
Estrogen receptor mutations in breast cancer
SAW Fuqua, GC Chamness… - Journal of cellular …, 1993 - Wiley Online Library
It is fairly well accepted that the presence of estrogen receptor (ER) identifies those breast
cancer patients with a lower risk of relapse and better overall survival [Clark and McGuire …
cancer patients with a lower risk of relapse and better overall survival [Clark and McGuire …
Quantification of estrogen receptor α and β expression in sporadic breast cancer
I Bièche, B Parfait, I Laurendeau, I Girault, M Vidaud… - Oncogene, 2001 - nature.com
The recent cloning of a second estrogen receptor (ER), designated ERβ, has prompted a
reevaluation of the role of ERs in breast cancer. We have developed and validated a real …
reevaluation of the role of ERs in breast cancer. We have developed and validated a real …