Elexacaftor-tezacaftor-ivacaftor increases airway nitric oxide in children with cystic fibrosis
Elexacaftor-tezacaftor-ivacaftor increases airway nitric oxide in children with cystic fibrosis J …

Airways of patients with cystic fibrosis are deficient for nitric oxide. Low nitric oxide in cystic
fibrosis has been shown to be associated with poor pulmonary function and risk of infection …

Introduction: Airway nitric oxide (FENO) in people with cystic fibrosis (CF) is lower than
normal and ivacaftor results in an early and sustained increase in FENO in treated …

Introduction: Nitric oxide (NO) plays an important role in the regulation of airway caliber &
host defense against certain bacteria. NO is reduced in cystic fibrosis (CF) airways & NO …

Objectives: In health, nitric oxide (NO) can be measured in high concentrations in the upper
respiratory tract. It has been shown that nasal NO (nNO) is significantly lower in patients with …

Background In health, nitric oxide (NO) shows high concentrations in the upper airways,
while nasal NO (nNO) is significantly lower in patients with sinonasal inflammation, such as …

Fractional exhaled nitric oxide (FeNO) has been reported to be reduced in cystic fibrosis
(CF) patients. However, data from young children are conflicting and it is not clear whether …

ETI treatment reduces inflammatory markers and positive bacterial cultures on BAL in PwCF.
These findings suggest that ETI has a greater impact on chronic infection and inflammation …

The fraction of exhaled nitric oxide (F eNO) is generally lower in individuals with cystic
fibrosis (CF), compared to healthy controls. Two recent studies reported that the cystic …

BACKGROUND Exhaled nitric oxide levels are low in patients with cystic fibrosis (CF),
despite the chronic inflammation present in the airways. This study aimed to determine …