Mechanical ventilation: state of the art

T Pham, LJ Brochard, AS Slutsky - Mayo Clinic Proceedings, 2017 - Elsevier
Mechanical ventilation is the most used short-term life support technique worldwide and is
applied daily for a diverse spectrum of indications, from scheduled surgical procedures to …

Clinical challenges in mechanical ventilation

EC Goligher, ND Ferguson, LJ Brochard - The Lancet, 2016 - thelancet.com
Mechanical ventilation supports gas exchange and alleviates the work of breathing when
the respiratory muscles are overwhelmed by an acute pulmonary or systemic insult …

A rational framework for selecting modes of ventilation

E Mireles-Cabodevila, U Hatipoğlu… - Respiratory Care, 2013 - rc.rcjournal.com
Mechanical ventilation is a life-saving intervention for respiratory failure and thus has
become the cornerstone of the practice of critical care medicine. A mechanical ventilation …

[HTML][HTML] Clinical strategies for implementing lung and diaphragm-protective ventilation: avoiding insufficient and excessive effort

EC Goligher, AH Jonkman, J Dianti, K Vaporidi… - Intensive care …, 2020 - Springer
Mechanical ventilation may have adverse effects on both the lung and the diaphragm. Injury
to the lung is mediated by excessive mechanical stress and strain, whereas the diaphragm …

The physiological underpinnings of life-saving respiratory support

I Telias, LJ Brochard, S Gattarello, H Wunsch… - Intensive care …, 2022 - Springer
Abstract Treatment of respiratory failure has improved dramatically since the polio epidemic
in the 1950s with the use of invasive techniques for respiratory support: mechanical …

History of mechanical ventilation. From Vesalius to ventilator-induced lung injury

AS Slutsky - American journal of respiratory and critical care …, 2015 - atsjournals.org
Mechanical ventilation is a life-saving therapy that catalyzed the development of modern
intensive care units. The origins of modern mechanical ventilation can be traced back about …

Ventilatory failure, ventilator support, and ventilator weaning

MJ Tobin, F Laghi, A Jubran - Comprehensive Physiology, 2012 - Wiley Online Library
The development of acute ventilatory failure represents an inability of the respiratory control
system to maintain a level of respiratory motor output to cope with the metabolic demands of …

Evidence-based guidelines for weaning and discontinuing ventilatory support: a collective task force facilitated by the American College of Chest Physicians; the …

NR MacIntyre - Chest, 2001 - journal.chestnet.org
Patients require mechanical ventilatory support when the ventilatory and/or gas exchange
capabilities of their respiratory system fail. This failure can be the result of processes both …

Work of breathing

B Cabello, J Mancebo - Intensive care medicine, 2006 - Springer
The main goal of mechanical ventilation is to help restore gas exchange and reduce the
work of breathing (WOB) by assisting respiratory muscle activity. Knowing the determinants …

Essentials of mechanical ventilation

D Hess, RM Kacmarek - 2002 - aacn.org
This practical guide is written from the perspective of authors who have nearly 100 years'
experience as clinicians, educators, researchers, and authors. Unlike other references on …