Human immunodeficiency virus (HIV) infection of brain macrophages and astroglial
proliferation are central features of HIV-induced central nervous system (CNS) disorders …

HIV-1-infected brain macrophages participate in neurologic dysfunction through their
continual secretion of neurotoxins. We previously demonstrated that astroglial cells activate …

Human immunodeficiency virus type 1 (HIV‐1) infection of the central nervous system is
associated with characteristic virological, clinical, and neuropathological findings in adults …

Recent studies in our laboratory and that of Dr. Howard Gendelman have revealed two
important pathways for neuronal damage during HIV-1 encephalopathy in children. First …

Hallmarks of central nervous system (GNS) disease in AIDS patients are headaches, fever,
subtle cognitive changes, abnormal reflexes, and ataxia. Dementia and severe sensory and …

HIV infection in brain revolves around productive viral replication in cells of mononuclear
phagocyte lineage, including brain macrophages, microglia, and multinucleated giant cells …

Neurological disease frequently complicates HIV-1 infection. In addition to opportunistic
infections, a syndrome of combined cognitive and motor impairment, referred to as the AIDS …

The etiology of the central nervous system (CNS) alterations after human immunodeficiency
virus (HIV) infection, such as dementia and encephalitis, remains unknown. We have used …

Neurological sequelae of human immunodeficiency virus (HIV) infection have been and
remain a significant problem. Monocytes and macrophages in humans and monkeys are …

The mechanisms by which human immunodeficiency virus (HIV) infection provokes
progressive neurodegener-ation and dementia in acquired immunodeficiency syndrome …