Sesquiterpenoids lactones: benefits to plants and people

M Chadwick, H Trewin, F Gawthrop… - International journal of …, 2013 - mdpi.com
Sesquiterpenoids, and specifically sesquiterpene lactones from Asteraceae, may play a
highly significant role in human health, both as part of a balanced diet and as …

Sesquiterpenoid lactones as potential anti-cancer agents: an update on molecular mechanisms and recent studies

P Dhyani, P Sati, E Sharma, DC Attri… - Cancer Cell …, 2022 - Springer
Plants-based natural compounds are well-identified and recognized chemoprotective
agents that can be used for primary and secondary cancer prevention, as they have proven …

What made sesquiterpene lactones reach cancer clinical trials?

A Ghantous, H Gali-Muhtasib, H Vuorela, NA Saliba… - Drug discovery today, 2010 - Elsevier
Sesquiterpene lactones (SLs) are plant-derived compounds often used in traditional
medicine against inflammation and cancer. This review focuses on the chemical and …

Anti-inflammatory and immunoregulatory action of sesquiterpene lactones

A Paço, T Brás, JO Santos, P Sampaio, AC Gomes… - Molecules, 2022 - mdpi.com
Sesquiterpene lactones (SL), characterized by their high prevalence in the Asteraceae
family, are one of the major groups of secondary metabolites found in plants. Researchers …

Biological activities of sesquiterpene lactones

AK Picman - Biochemical systematics and Ecology, 1986 - Elsevier
Although sesquiterpene lactones are terpenoid compounds characteristic of the Asteraceae
(Compositae) they are also known from other angiosperm families as well as from some …

[PDF][PDF] Sesquiterpene lactones: structural diversity and their biological activities, In-Opportunity, Challanges and Scope of Natural Products in Medicinal Chemistry

D Chaturvedi - ISBN: 978-81-308-0448-4, Research Signpost …, 2011 - core.ac.uk
Sesquiterpenes lactones (SLs) have been isolated from numerous genera of the family
Asteraceae (compositae) and can also be found in other angiosperm families. They are …

Perspectives on sesquiterpene lactones in inflammation and cancer

I Merfort - Current drug targets, 2011 - ingentaconnect.com
Sesquiterpene lactones are a large group of secondary plant metabolites mostly known from
the Asteraceae family. They exert a broad variety of different biological activities. This review …

Sesquiterpene lactones: Promising natural compounds to fight inflammation

MS Matos, JD Anastácio, C Nunes dos Santos - Pharmaceutics, 2021 - mdpi.com
Inflammation is a crucial and complex process that reestablishes the physiological state after
a noxious stimulus. In pathological conditions the inflammatory state may persist, leading to …

Anti-cancer potential of sesquiterpene lactones: bioactivity and molecular mechanisms

S Zhang, YK Won, CN Ong… - … Medicinal Chemistry-Anti …, 2005 - ingentaconnect.com
Sesquiterpene lactones (SLs) are the active constituents of a variety of medicinal plants
used in traditional medicine for the treatment of inflammatory diseases. In recent years, the …

Sesquiterpenes and their derivatives-natural anticancer compounds: An update

T Abu-Izneid, A Rauf, MA Shariati, AA Khalil… - Pharmacological …, 2020 - Elsevier
Sesquiterpenes belong to the largest group of plant secondary metabolites, which consist of
three isoprene building units. These compounds are widely distributed in various …