Background: Epigenetic modifications, such as DNA methylation, due to in utero exposures
may play a critical role in early programming for childhood and adult illness. Maternal …

Background: Maternal smoking during pregnancy is associated with significant infant
morbidity and mortality, and may influence later disease risk. One mechanism by which …

Aim: Cigarette smoking influences DNA methylation genome wide, in newborns from
pregnancy exposure and in adults from personal smoking. Whether a unique methylation …

Background: Prenatal exposure to maternal cigarette smoking (prenatal smoke exposure)
had been associated with altered DNA methylation (DNAm) at birth. Objective: We examined …

Epigenetic modifications, including DNA methylation, represent a potential mechanism for
environmental impacts on human disease. Maternal smoking in pregnancy remains an …

Background Maternal smoking during pregnancy is a major risk factor for adverse health
outcomes. The main objective of the study was to assess the impact of in utero tobacco …

Mounting evidence links prenatal exposure to maternal tobacco smoking with disruption of
DNA methylation (DNAm) profile in the blood of infants. However, data on the postnatal …

Background Cigarette smoking has severe adverse health consequences in adults and in
the offspring of mothers who smoke during pregnancy. One of the most widely reported …

Background: We conducted an epigenome-wide association study (EWAS) of DNA
methylation in placenta in relation to maternal tobacco smoking during pregnancy and …

Background: Maternal smoking in pregnancy is associated with adverse health outcomes in
children, including cancers; underlying mechanisms may include epigenetic modifications …