[HTML][HTML] Streamlined Synthesis of 6-((1H-1,2,3-Triazol-4-yl)methyl)-1H-pyrrolo [3,4-d]pyridazin-1-one System via Sequential N-Alkylation, CuAAC, and [4 + 2] …
HG Bonacorso, HT Magalhães, GMD Forno… - Journal of the Brazilian …, 2019 - SciELO Brasil
An efficient sequential three-step reaction methodology for the synthesis of three new series-
1-(prop-2-yn-1-yl)-1H-pyrroles, methyl 4-acetyl-1-((1H-1, 2, 3-triazol-4-yl) methyl)-1H-pyrrole …
1-(prop-2-yn-1-yl)-1H-pyrroles, methyl 4-acetyl-1-((1H-1, 2, 3-triazol-4-yl) methyl)-1H-pyrrole …
New Convenient Four-Component Synthesis of 6-Amino-2, 4-dihydropyrano [2, 3-c] pyrazol-5-carbonitriles and One-Pot Synthesis of 6′-Aminospiro [(3 H)-indol-3, 4 …
YM Litvinov, AA Shestopalov… - Journal of …, 2009 - ACS Publications
This report describes a new four-component synthesis of substituted and spiro-conjugated 6-
amino-2 H, 4 H-pyrano [2, 3-c] pyrazol-5-carbonitriles directly from aromatic aldehydes or …
amino-2 H, 4 H-pyrano [2, 3-c] pyrazol-5-carbonitriles directly from aromatic aldehydes or …
Four-Component Domino Strategy for the Combinatorial Synthesis of Novel 1,4-Dihydropyrano[2,3-c]pyrazol-6-amines
S Kanchithalaivan, S Sivakumar… - ACS Combinatorial …, 2013 - ACS Publications
An efficient one-pot four-component domino protocol for the combinatorial synthesis of novel
1, 4-dihydropyrano [2, 3-c] pyrazol-6-amines has been achieved. This transformation …
1, 4-dihydropyrano [2, 3-c] pyrazol-6-amines has been achieved. This transformation …
One-pot synthesis of [1, 2, 3] triazole-fused pyrazinopyridazindione tricycles by a 'click and activate'approach
W Qian, D Winternheimer, A Amegadzie, J Allen - Tetrahedron letters, 2012 - Elsevier
Substituted [1, 2, 3] triazole-fused pyrazinopyridazindione tricycles were synthesized in a
four-component, stepwise condensation. The key step in this one-pot process was a thermal …
four-component, stepwise condensation. The key step in this one-pot process was a thermal …
[HTML][HTML] Synthesis of tris-heterocycles via a cascade IMCR/aza Diels-Alder+ CuAAC strategy
MA Rentería-Gómez, A Islas-Jácome… - Frontiers in …, 2019 - frontiersin.org
6-Triazolylmethyl-pyrrolo [3, 4-b] pyridin-5-one tris-heterocycles were synthesized in 43–
57% overall yields. The two-stage synthesis involved a cascade process (Ugi-3CR/aza Diels …
57% overall yields. The two-stage synthesis involved a cascade process (Ugi-3CR/aza Diels …
One-pot synthesis of novel 1-(1H-tetrazol-5-yl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine derivatives via an Ugi-azide 4CR process
A facile one-pot method has been developed for the synthesis of novel pyrrolo [2, 1-a]
pyrazine scaffolds. A variety of 1-(1 H-tetrazol-5-yl)-1, 2, 3, 4-tetrahydropyrrolo [1, 2-a] …
pyrazine scaffolds. A variety of 1-(1 H-tetrazol-5-yl)-1, 2, 3, 4-tetrahydropyrrolo [1, 2-a] …
[HTML][HTML] Synthesis of New Polyheterocyclic Pyrrolo[3,4-b]pyridin-5-ones via an Ugi-Zhu/Cascade/Click Strategy
RE Blanco-Carapia, EA Aguilar-Rangel… - Molecules, 2023 - mdpi.com
A diversity-oriented synthesis (DOS) of two new polyheterocyclic compounds was performed
via an Ugi-Zhu/cascade (N-acylation/aza Diels-Alder cycloaddition/decarboxylation …
via an Ugi-Zhu/cascade (N-acylation/aza Diels-Alder cycloaddition/decarboxylation …
Post-Ugi carbocyclization/fragmentation sequence for the synthesis of 6, 7-dihydro-5H-pyrrolo [3, 4-b] pyridin-5-ones
TTT Trang, AA Peshkov, J Jacobs, L Van Meervelt… - Tetrahedron …, 2015 - Elsevier
A two-step one-pot sequence, involving Ugi reaction followed by base-promoted
carbocyclization accompanied by cleavage of the isocyanide-originated amide moiety, has …
carbocyclization accompanied by cleavage of the isocyanide-originated amide moiety, has …
A Convenient Synthesis of 2H‐Pyran‐2‐ones, Fused Pyran‐2‐ones, and Pyridones Bearing a Thiazole Moiety
S Bondock, AEG Tarhoni… - Journal of Heterocyclic …, 2014 - Wiley Online Library
The versatile enaminonitrile, 2‐cyano‐3‐(dimethylamino)‐N‐(4‐phenylthiazol‐2‐yl)‐
acrylamide (2), reacts with some C, O‐binucleophiles (acetylacetone and dimedone) in …
acrylamide (2), reacts with some C, O‐binucleophiles (acetylacetone and dimedone) in …
Efficient Synthesis of Pyrrolo [2, 3‐d] Pyrimidines Containing 1, 4‐Disubstituted‐1, 2, 3‐Triazole Derivatives
R Ruddarraju, AC Murugulla… - Journal of …, 2017 - Wiley Online Library
Here, we demonstrate a simple but highly efficient method for the synthesis of
multifunctionalized pyrrolo [2, 3‐d] pyrimidines containing 1, 4‐disubstituted 1, 2, 3‐triazole …
multifunctionalized pyrrolo [2, 3‐d] pyrimidines containing 1, 4‐disubstituted 1, 2, 3‐triazole …