[HTML][HTML] Structure–activity features of purines and their receptors: Implications in cell physiopathology
M Díaz-Muñoz, R Hernández-Muñoz… - Molecular …, 2022 - Springer
The purine molecular structure consists of fused pyrimidine and imidazole rings. Purines are
main pieces that conform the structure of nucleic acids which rule the inheritance processes …
main pieces that conform the structure of nucleic acids which rule the inheritance processes …
[HTML][HTML] From purines to purinergic signalling: molecular functions and human diseases
Purines and their derivatives, most notably adenosine and ATP, are the key molecules
controlling intracellular energy homoeostasis and nucleotide synthesis. Besides, these …
controlling intracellular energy homoeostasis and nucleotide synthesis. Besides, these …
Purinergic approaches in experimental therapeutics
KA Jacobson, MF Jarvis - European Journal of Medicinal Chemistry, 1997 - infona.pl
This book deals with scientific data defining the role of purines and pyrimidines in various
diseases. The respective roles of adenosine and ATP and their respective recognition sites …
diseases. The respective roles of adenosine and ATP and their respective recognition sites …
Purine and purinergic receptors in health and disease
Y Ai, H Wang, L Liu, Y Qi, S Tang, J Tang, N Chen - MedComm, 2023 - Wiley Online Library
Purines and purinergic receptors are widely distributed throughout the human body. Purine
molecules within cells play crucial roles in regulating energy metabolism and other cellular …
molecules within cells play crucial roles in regulating energy metabolism and other cellular …
[HTML][HTML] Purinergic signaling: Diverse effects and therapeutic potential in cancer
J Kaur, S Dora - Frontiers in Oncology, 2023 - frontiersin.org
Regardless of improved biological insights and therapeutic advances, cancer is consuming
multiple lives worldwide. Cancer is a complex disease with diverse cellular, metabolic, and …
multiple lives worldwide. Cancer is a complex disease with diverse cellular, metabolic, and …
Purines, purinergic receptors, and cancer
F Di Virgilio - Cancer research, 2012 - AACR
Purines were long thought to be restricted to the intracellular compartment, where they are
used for energy transactions, nucleic acid synthesis, and a multiplicity of biochemical …
used for energy transactions, nucleic acid synthesis, and a multiplicity of biochemical …
[HTML][HTML] Extracellular adenosine signaling in molecular medicine
HK Eltzschig - Journal of Molecular Medicine, 2013 - Springer
Biochemically, adenosine belongs to a group of molecules referred to as purines. Purines
are heterocyclic aromatic molecules that are among the oldest and most influential …
are heterocyclic aromatic molecules that are among the oldest and most influential …
An insight into the rational design of recent purine-based scaffolds in targeting various cancer pathways
A Chaurasiya, SK Wahan, C Sahu… - Journal of Molecular …, 2023 - Elsevier
Impacting the lives of millions throughout the globe, cancer is the world's leading cause of
death. In cancer treatment and prognosis, a number of anticancer medicines have been …
death. In cancer treatment and prognosis, a number of anticancer medicines have been …
[图书][B] Pharmacology of purine and pyrimidine receptors
J Linden, KA Jacobson - 2011 - books.google.com
This is an overview of the fast-moving field of purinergic signalling through adenosine and
ATP receptors. Authors are the leading authorities in their fields Subject matter is important …
ATP receptors. Authors are the leading authorities in their fields Subject matter is important …
Receptors for purines and pyrimidines
V Ralevic, G Burnstock - Pharmacological reviews, 1998 - ASPET
Extracellular purines (adenosine, ADP, and ATP) and pyrimidines (UDP and UTP) are
important signaling molecules that mediate diverse biological effects via cellsurface …
important signaling molecules that mediate diverse biological effects via cellsurface …