Irritable bowel syndrome (IBS) is the most prevalent disorder of brain-gut interactions that
affects between 5 and 10% of the general population worldwide. The current symptom …

Objective To improve the pathophysiological understanding of irritable bowel syndrome
(IBS) by exploring the gut-brain axis. Background Disorders of gut-brain interaction (DGBIs) …

Patients with irritable bowel syndrome (IBS) are increasingly presenting with a wide range of
neuropsychiatric symptoms, such as deterioration in gastroenteric physiology, including …

Irritable bowel syndrome (IBS) is characterized by abdominal pain and altered bowel habits.
Visceral hypersensitivity is believed to be a key underlying mechanism that causes pain …

Irritable bowel syndrome (IBS) is one of the most common of all medical disorders worldwide
and, while for some it represents no more than a nuisance, for others it imposes significant …

Irritable bowel syndrome (IBS) is a functional syndrome characterized by chronic abdominal
pain accompanied by altered bowel habits. Although generally considered a functional …

Alterations in the bidirectional interactions between the intestine and the nervous system
have important roles in the pathogenesis of irritable bowel syndrome (IBS). A body of largely …

Irritable bowel syndrome (IBS) is a common gastrointestinal disorder with an estimated
prevalence of 10–20%. Current understanding of the pathophysiology of IBS is incomplete …

The gastrointestinal tract is a vast neuroendocrine organ with extensive extrinsic and
intrinsic neural circuits that interact to control its function. Circulating and paracrine …

Irritable bowel syndrome (IBS) is an extremely prevalent but poorly understood
gastrointestinal disorder. Consequently, there are no clear diagnostic markers to help …