Glaucoma treatment and hydrogel: Current insights and state of the art

AM Fea, C Novarese, P Caselgrandi, G Boscia - Gels, 2022 - mdpi.com
Aqueous gels formulated using hydrophilic polymers (hydrogels) and those based on stimuli-
responsive polymers (in situ gelling or gel-forming systems) attract increasing interest in the …

Ophthalmic gels: Past, present and future

AA Al-Kinani, G Zidan, N Elsaid, A Seyfoddin… - Advanced drug delivery …, 2018 - Elsevier
Aqueous gels formulated using hydrophilic polymers (hydrogels) along with those based on
stimuli responsive polymers (in situ gelling or gel forming systems) continue to attract …

Biocompatible in-situ gelling polymer hydrogels for treating ocular infection

M Sharma, A Deohra, KR Reddy, V Sadhu - Methods in Microbiology, 2019 - Elsevier
The eye is a sensitive organ susceptible to bacterial as well as fungal acute and chronic
infections. Commonly used conventional ocular dosage forms are solutions, drops …

Applications and recent developments of Hydrogels in Ophthalmology

X Wang, FQ Li, X Liu, H Zhang - ACS Biomaterials Science & …, 2023 - ACS Publications
Hydrogels are a type of functional polymer material with a three-dimensional network
structure composed of physically or chemically cross-linked polymers. All hydrogels have …

Hydrogels in ophthalmology: Novel strategies for overcoming therapeutic challenges

KY Wu, D Akbar, M Giunta, A Kalevar, SD Tran - Materials, 2023 - mdpi.com
The human eye's intricate anatomical and physiological design necessitates tailored
approaches for managing ocular diseases. Recent advancements in ophthalmology …

Potential of stimuli-responsive in situ gel system for sustained ocular drug delivery: Recent progress and contemporary research

M Pandey, H Choudhury, A binti Abd Aziz… - Polymers, 2021 - mdpi.com
Eyesight is one of the most well-deserved blessings, amid all the five senses in the human
body. It captures the raw signals from the outside world to create detailed visual images …

Hydrogel-based ocular drug delivery systems: Emerging fabrication strategies, applications, and bench-to-bedside manufacturing considerations

RC Cooper, H Yang - Journal of controlled release, 2019 - Elsevier
The physiological barriers of the eye pose challenges to the delivery of the array of
therapeutics for ocular diseases. Hydrogels have been widely explored for medical …

Gel-based materials for ophthalmic drug delivery

R Cassano, ML Di Gioia, S Trombino - Gels, 2021 - mdpi.com
The most common route of administration of ophthalmic drugs is the topical route because it
is convenient, non-invasive, and accessible to all patients. Unfortunately, drugs …

Intravitreal injectable hydrogels for sustained drug delivery in glaucoma treatment and therapy

KA Akulo, T Adali, MTG Moyo, T Bodamyali - Polymers, 2022 - mdpi.com
Glaucoma is extensively treated with topical eye drops containing drugs. However, the
retention time of the loaded drugs and the in vivo bioavailability of the drugs are highly …

Hydrogels in ophthalmic applications

S Kirchhof, AM Goepferich, FP Brandl - European Journal of Pharmaceutics …, 2015 - Elsevier
More and more people worldwide are affected by severe eye diseases eventually leading to
visual impairment or blindness. In most cases, the treatment involves the application of …