Development and clinical validation of a novel 9-gene prognostic model based on multi-omics in pancreatic adenocarcinoma

D Xu, Y Wang, X Liu, K Zhou, J Wu, J Chen… - Pharmacological …, 2021 - Elsevier
The prognoses of patients with pancreatic adenocarcinoma (PAAD) remain poor due to the
lack of biomarkers for early diagnosis and effective prognosis prediction. RNA sequencing …

[HTML][HTML] A 6‑gene risk score system constructed for predicting the clinical prognosis of pancreatic adenocarcinoma patients

Y Liu, D Zhu, H Xing, Y Hou, Y Sun - Oncology Reports, 2019 - spandidos-publications.com
Pancreatic adenocarcinoma (PAC) is the most common type of pancreatic cancer, which
commonly has an unfavorable prognosis. The present study aimed to develop a novel …

[HTML][HTML] Identification of a nine-gene signature and establishment of a prognostic nomogram predicting overall survival of pancreatic cancer

M Wu, X Li, T Zhang, Z Liu, Y Zhao - Frontiers in oncology, 2019 - frontiersin.org
Background: Pancreatic cancer is highly lethal and aggressive with increasing trend of
mortality in both genders. An effective prediction model is needed to assess prognosis of …

[HTML][HTML] Prediction of survival and recurrence in patients with pancreatic cancer by integrating multi-omics data

B Baek, H Lee - Scientific reports, 2020 - nature.com
Predicting the prognosis of pancreatic cancer is important because of the very low survival
rates of patients with this particular cancer. Although several studies have used microRNA …

Importance of gene expression signatures in pancreatic cancer prognosis and the establishment of a prediction model

X Yan, H Wan, X Hao, T Lan, W Li, L Xu… - Cancer management …, 2018 - Taylor & Francis
Background and aim Pancreatic cancer (PC) is one of the most common tumors with a poor
prognosis. The current American Joint Committee on Cancer (AJCC) staging system, based …

[HTML][HTML] Development of a four-gene prognostic model for pancreatic cancer based on transcriptome dysregulation

J Yan, L Wu, C Jia, S Yu, Z Lu, Y Sun, J Chen - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
We systematically developed a prognostic model for pancreatic cancer that was compatible
across different transcriptomic platforms and patient cohorts. After performing quality control …

Development of a 12-biomarkers-based prognostic model for pancreatic cancer using multi-omics integrated analysis

Y Jia, M Shen, Y Zhou, H Liu - Acta Biochimica Polonica, 2020 - abp.ptbioch.edu.pl
Pancreatic cancer is one of the most malignant tumors of the digestive system, with
insidious, rapid onset and high mortality. The 5-year survival rate is only 10%. Therefore, in …

[HTML][HTML] Construction of a prognostic prediction system for pancreatic ductal adenocarcinoma to investigate the key prognostic genes

B Zheng, J Peng, A Mollayup… - Molecular …, 2018 - spandidos-publications.com
Pancreatic cancer (PC) is associated with high mortality rates and poor prognoses.
Pancreatic adenocarcinoma is the most common type of PC, and almost all cases of …

[HTML][HTML] A thirteen-gene expression signature predicts survival of patients with pancreatic cancer and identifies new genes of interest

TE Newhook, EM Blais, JM Lindberg, SJ Adair, W Xin… - PloS one, 2014 - journals.plos.org
Background Currently, prognostication for pancreatic ductal adenocarcinoma (PDAC) is
based upon a coarse clinical staging system. Thus, more accurate prognostic tests are …

[HTML][HTML] A novel tp53-associated nomogram to predict the overall survival in patients with pancreatic cancer

X Liu, B Chen, J Chen, S Sun - BMC cancer, 2021 - Springer
Background Gene mutations play critical roles in tumorigenesis and cancer development.
Our study aimed to screen survival-related mutations and explore a novel gene signature to …