Mounting evidence suggests a role for mitochondrial dysfunction in the pathogenesis of
many diseases, including type 2 diabetes, aging, and ovarian failure. Because of the central …

Polycystic ovary syndrome (PCOS) is a complex, but relatively common endocrine disorder
associated with chronic anovulation, hyperandrogenism, and micro-polycystic ovaries. In …

Mitochondria are fundamental for oxidative energy production and impairment of their
functionality can lead to reduced ATP synthesis and contribute to initiation of apoptosis …

Mitochondrial damage is implicated as a major contributing factor for a number of
noncommunicable chronic diseases such as cardiovascular diseases, cancer, obesity, and …

In the last decade, there has been an increased appreciation for mitochondria as central
hubs in diverse processes, such as cellular energy, immunity, and signal transduction. As …

Mitochondria, the cell's powerhouses, produce up to 95% of a eukaryotic cell's energy (ATP)
through oxidative phosphorylation to fuel cellular activity. They are also highly dynamic …

Obesity is associated with ovulatory disorders, decreased rates of conception, infertility,
early pregnancy loss and congenital abnormalities. Poor oocyte quality and reduced IVF …

The ability of an organism to convert organic molecules from the environment into energy is
essential for the development of cellular structures, cell differentiation and growth …

Research in the last decade has revolutionized the way in which we view mitochondria.
Mitochondria are no longer viewed solely as cellular powerhouses; rather, mitochondria are …

Mitochondria are critical organelles for endocrine health; steroid hormone biosynthesis
occurs in these organelles and they provide energy in the form of ATP for hormone …