Extracellular matrix-based materials for regenerative medicine

GS Hussey, JL Dziki, SF Badylak - Nature Reviews Materials, 2018 - nature.com
In tissue engineering and regenerative medicine, a biomaterial provides mechanical support
and biochemical signals to encourage cell attachment and modulate cell behaviour …

[HTML][HTML] Preparation and use of decellularized extracellular matrix for tissue engineering

AD McInnes, MAJ Moser, X Chen - Journal of functional biomaterials, 2022 - mdpi.com
The multidisciplinary fields of tissue engineering and regenerative medicine have the
potential to revolutionize the practise of medicine through the abilities to repair, regenerate …

Cell-derived matrices for tissue engineering and regenerative medicine applications

LE Fitzpatrick, TC McDevitt - Biomaterials science, 2015 - pubs.rsc.org
The development and application of decellularized extracellular matrices (ECM) has grown
rapidly in the fields of cell biology, tissue engineering and regenerative medicine in recent …

Extracellular matrix as a biological scaffold material: Structure and function

SF Badylak, DO Freytes, TW Gilbert - Acta biomaterialia, 2009 - Elsevier
Biological scaffold materials derived from the extracellular matrix (ECM) of intact mammalian
tissues have been successfully used in a variety of tissue engineering/regenerative …

Tissue-specific parameters for the design of ECM-mimetic biomaterials

OR Tonti, H Larson, SN Lipp, CM Luetkemeyer… - Acta biomaterialia, 2021 - Elsevier
The extracellular matrix (ECM) is a complex network of biomolecules that mechanically and
biochemically directs cell behavior and is crucial for maintaining tissue function and health …

[HTML][HTML] Engineering ECM signals into biomaterials

RJ Wade, JA Burdick - Materials Today, 2012 - Elsevier
Historically, tissue engineering focused primarily on the delivery of soluble factors within
relatively static scaffolds; yet, increasing evidence indicates that the native, dynamic three …

Extracellular matrix-derived biomaterials in engineering cell function

H Xing, H Lee, L Luo, TR Kyriakides - Biotechnology advances, 2020 - Elsevier
Extracellular matrix (ECM) derived components are emerging sources for the engineering of
biomaterials that are capable of inducing desirable cell-specific responses. This review …

Extracellular matrix as an inductive scaffold for functional tissue reconstruction

BN Brown, SF Badylak - Translational Research, 2014 - Elsevier
The extracellular matrix (ECM) is a meshwork of both structural and functional proteins
assembled in unique tissue-specific architectures. The ECM both provides the mechanical …

Leveraging “raw materials” as building blocks and bioactive signals in regenerative medicine

AN Renth, MS Detamore - Tissue Engineering Part B: Reviews, 2012 - liebertpub.com
Components found within the extracellular matrix (ECM) have emerged as an essential
subset of biomaterials for tissue engineering scaffolds. Collagen, glycosaminoglycans …

[HTML][HTML] Decellularized extracellular matrix mediates tissue construction and regeneration

C Liu, M Pei, Q Li, Y Zhang - Frontiers of medicine, 2022 - Springer
Contributing to organ formation and tissue regeneration, extracellular matrix (ECM)
constituents provide tissue with three-dimensional (3D) structural integrity and cellular …