The scototaxis (dark/light preference) protocol is a behavioral model for fish that is being
validated to assess the antianxiety effects of pharmacological agents and the behavioral …

Scototaxis, the preference for dark environments in detriment of bright ones, is an index of
anxiety in zebrafish. In this work, we analyzed avoidance of the white compartment by …

The light/dark box test, traditionally used to quantify rodent anxiety-like behavior, has
recently been applied to the adult zebrafish (Danio rerio). Utilizing the fish's scototaxis …

The scototaxis test has been introduced recently to assess anxiety-like phenotypes in fish,
including zebrafish. Parametric analyses suggest that scototaxis represents an approach …

The effects of wall color stimuli on diving, and the effects of depth stimuli on scototaxis, were
assessed in zebrafish. Three groups of fish were confined to a black, a white, or a …

While zebrafish may be a useful behavioral model of human anxiety, it is not obvious which
behaviors are accurate measures of anxiety in zebrafish. Beginning with the premise that the …

One of the most commonly used behavioral endpoints measured in preclinical studies using
rodent models is thigmotaxis (or “wall-hugging”). Thigmotaxis is a well-validated index of …

Background Larval zebrafish, with a simple and transparent vertebrate brain composed of~
100 K neurons, is well suited for deciphering entire neural circuit activity underlying …

The light/dark preference test is commonly used to assess anxiety-like phenotypes and
validate the pharmacological effects of neuroactive compounds. This test has been recently …

Zebrafish larvae are ideally suited for high-throughput analyses of vertebrate behavior. The
larvae can be examined in multiwell plates and display a range of behaviors during early …