Circular RNA circ-CPA4/let-7 miRNA/PD-L1 axis regulates cell growth, stemness, drug resistance and immune evasion in non-small cell lung cancer (NSCLC)

W Hong, M Xue, J Jiang, Y Zhang, X Gao - Journal of Experimental & …, 2020 - Springer
Background Non-small cell lung cancer (NSCLC) cells derived intracellular and extracellular
programmed cell death ligand 1 (PD-L1) promoted cancer progression and drug resistance …

Circular RNA circ_0000284 plays an oncogenic role in the progression of non-small cell lung cancer through the miR-377-3p-mediated PD-L1 promotion

L Li, Q Zhang, K Lian - Cancer Cell International, 2020 - Springer
Abstract Background Circular RNAs (circRNAs), a subgroup of non-coding RNAs, are
recognized as pivotal mediators in various types of cancers. CircRNA_0000284 …

Circular RNA hsa_circ_0004015 regulates the proliferation, invasion, and TKI drug resistance of non-small cell lung cancer by miR-1183/PDPK1 signaling pathway

Y Zhou, X Zheng, B Xu, L Chen, Q Wang… - Biochemical and …, 2019 - Elsevier
Circular RNAs (circRNAs) were recently reported to be involved in the pathogenesis of Non-
small cell lung cancer (NSCLC), however, the molecular mechanisms of circRNAs in cell …

CircRNA_101237 promotes NSCLC progression via the miRNA-490-3p/MAPK1 axis

Z Zhang, X Gao, M Ma, C Zhao, Y Zhang, S Guo - Scientific reports, 2020 - nature.com
Non-small cell lung cancer (NSCLC) is a common type of lung cancer, characterized by a
poor prognosis. In the last several years, more and more studies have demonstrated the …

Circular RNA circ_0001287 inhibits the proliferation, metastasis, and radiosensitivity of non-small cell lung cancer cells by sponging microRNA miR-21 and up …

CC Zhang, Y Li, XZ Feng, DB Li - Bioengineered, 2021 - Taylor & Francis
As a type of non-coding RNA, circular RNA (circRNA) figures prominently in human cancer
progression. Nonetheless, the expression, function, and regulatory mechanism of …

Circ_0076305 regulates cisplatin resistance of non-small cell lung cancer via positively modulating STAT3 by sponging miR-296–5p

Y Dong, T Xu, S Zhong, B Wang, H Zhang, X Wang… - Life sciences, 2019 - Elsevier
Abstract Aims Circular RNAs (circRNAs) acted as key regulators in the development of
various human tumors. Our present study aimed to investigate the role and molecular …

Circular RNA circPVT1 promotes proliferation and invasion through sponging miR-125b and activating E2F2 signaling in non-small cell lung cancer

X Li, Z Zhang, H Jiang, Q Li, R Wang, H Pan… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Circular RNAs (circRNAs) are key regulators in the development and
progression of human cancers, however its role in non-small cell lung cancer (NSCLC) …

[HTML][HTML] Circ_0067934 promotes non-small cell lung cancer development by regulating miR-1182/KLF8 axis and activating Wnt/β-catenin pathway

M Zhao, W Ma, C Ma - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Non-small cell lung cancer (NSCLC) is the primary subtype of lung cancer with high
mortality. Circular RNAs (circRNAs) play a crucial role in tumor development and …

Circular RNA circ_0074027 indicates a poor prognosis for NSCLC patients and modulates cell proliferation, apoptosis, and invasion via miR‐185‐3p mediated BRD4 …

P Gao, Z Wang, Z Hu, X Jiao… - Journal of cellular …, 2020 - Wiley Online Library
Circular RNAs play an imperative role in cancer development and metastasis by regulating
oncogenic and tumor‐suppressive pathways. However, the role and mechanism of …

[HTML][HTML] Circular RNA PVT1 acts as a competing endogenous RNA for miR-497 in promoting non-small cell lung cancer progression

S Qin, Y Zhao, G Lim, H Lin, X Zhang… - Biomedicine & …, 2019 - Elsevier
Circular RNAs (circRNAs) are a class of covalently closed non-coding RNAs and play
crucial regulatory roles in human cancer biology. The purpose of the present study was to …