Advanced maternal age in IVF: still a challenge? The present and the future of its treatment

FM Ubaldi, D Cimadomo, A Vaiarelli… - Frontiers in …, 2019 - frontiersin.org
Advanced maternal age (AMA;> 35 year) is associated with a decline in both ovarian
reserve and oocyte competence. At present, no remedies are available to counteract the …

Impact of maternal age on oocyte and embryo competence

D Cimadomo, G Fabozzi, A Vaiarelli, N Ubaldi… - Frontiers in …, 2018 - frontiersin.org
The overall success of human reproduction, either spontaneously or after IVF, is highly
dependent upon maternal age. The main reasons for age-related infertility include reduced …

The root of reduced fertility in aged women and possible therapentic options: current status and future perspects

J Qiao, ZB Wang, HL Feng, YL Miao, Q Wang… - Molecular aspects of …, 2014 - Elsevier
It is well known that maternal ageing not only causes increased spontaneous abortion and
reduced fertility, but it is also a high genetic disease risk. Although assisted reproductive …

Improvements in IVF in women of advanced age

N Gleicher, VA Kushnir, DF Albertini… - Journal of …, 2016 - joe.bioscientifica.com
Women above age 40 years in the US now represent the most rapidly growing age group
having children. Patients undergoing in vitro fertilization (IVF) are rapidly aging in parallel …

Reproductive aging and elective fertility preservation

R Fritz, S Jindal - Journal of ovarian research, 2018 - Springer
Reproductive aging is a natural process that occurs in all women, eventually leading to
reproductive senescence and menopause. Over the past half century there has been a trend …

Assisted conception in women of advanced maternal age

S Seshadri, G Morris, P Serhal, W Saab - Best Practice & Research Clinical …, 2021 - Elsevier
A delay in childbearing to later in life has increased the number of women of advanced
maternal age (AMA) opting for assisted reproduction. Women should be made aware that …

What is the best regimen for ovarian stimulation of poor responders in ART/IVF?

Z Blumenfeld - Frontiers in endocrinology, 2020 - frontiersin.org
The infertile patients with aging ovaries—also sometimes referred to as impending
premature ovarian insufficiency (POI), impending premature ovarian failure (POF), or poor …

Assisted reproduction in women over 40 years of age: how old is too old?

A Hourvitz, R Machtinger, E Maman, M Baum… - Reproductive …, 2009 - Elsevier
Women's fertility progressively declines with advanced age due to depletion of the ovarian
follicular reserve and poorer oocyte quality. However, many women of advanced age are …

Advanced reproductive age and fertility: no. 269, November 2011

K Liu, A Case, AP Cheung, S Sierra… - … of Gynecology & …, 2012 - Wiley Online Library
Objective To improve awareness of the natural age‐related decline in female and male
fertility with respect to natural fertility and assisted reproductive technologies (ART) and …

Biological versus chronological ovarian age: implications for assisted reproductive technology

C Alviggi, P Humaidan, CM Howles, D Tredway… - Reproductive Biology …, 2009 - Springer
Background Women have been able to delay childbearing since effective contraception
became available in the 1960s. However, fertility decreases with increasing maternal age. A …