Current uses of artificial intelligence in the analysis of biofluid markers involved in corneal and ocular surface diseases: a systematic review

DR Pur, SH Krance, A Pucchio, RN Miranda, T Felfeli - Eye, 2023 - nature.com
Corneal and ocular surface diseases (OSDs) carry significant psychosocial and economic
burden worldwide. We set out to review the literature on the application of artificial …

Applications of artificial intelligence and bioinformatics methodologies in the analysis of ocular biofluid markers: a scoping review

A Pucchio, SH Krance, DR Pur, J Bhatti, A Bassi… - Graefe's Archive for …, 2024 - Springer
Purpose This scoping review summarizes the applications of artificial intelligence (AI) and
bioinformatics methodologies in analysis of ocular biofluid markers. The secondary objective …

[HTML][HTML] Artificial intelligence analysis of biofluid markers in age-related macular degeneration: a systematic review

A Pucchio, SH Krance, DR Pur… - Clinical …, 2022 - ncbi.nlm.nih.gov
This systematic review explores the use of artificial intelligence (AI) in the analysis of biofluid
markers in age-related macular degeneration (AMD). We detail the accuracy and validity of …

Emerging applications of bioinformatics and artificial intelligence in the analysis of biofluid markers involved in retinal occlusive diseases: a systematic review

DR Pur, S Krance, A Pucchio, A Bassi… - Graefe's Archive for …, 2023 - Springer
Purpose To review the literature on the application of bioinformatics and artificial intelligence
(AI) for analysis of biofluid biomarkers in retinal vein occlusion (RVO) and their potential …

Tear fluid biomarkers in ocular and systemic disease: potential use for predictive, preventive and personalised medicine

S Hagan, E Martin, A Enríquez-de-Salamanca - Epma Journal, 2016 - Springer
In the field of predictive, preventive and personalised medicine, researchers are keen to
identify novel and reliable ways to predict and diagnose disease, as well as to monitor …

Mass spectrometry analysis of human tear fluid biomarkers specific for ocular and systemic diseases in the context of 3P medicine

X Zhan, J Li, Y Guo, O Golubnitschaja - EPMA Journal, 2021 - Springer
Over the last two decades, a large number of non-communicable/chronic disorders reached
an epidemic level on a global scale such as diabetes mellitus type 2, cardio-vascular …

Tear analysis in ocular surface diseases

L Zhou, RW Beuerman - Progress in retinal and eye research, 2012 - Elsevier
The thin layer of tears covering the ocular surface are a complex body fluid containing
thousands of molecules of varied form and function of several origins. In this review, we …

Identification of tear fluid biomarkers in dry eye syndrome using iTRAQ quantitative proteomics

L Zhou, RW Beuerman, CM Chan… - Journal of proteome …, 2009 - ACS Publications
The proteins found in tears have an important role in the maintenance of the ocular surface
and changes in the quality and quantity of tear components reflect changes in the health of …

Integrated Analysis of Transcriptome and Proteome of the Human Cornea and Aqueous Humor Reveal Novel Biomarkers for Corneal Endothelial Cell Dysfunction

CE Moon, CH Kim, JH Jung, YJ Cho, KY Choi… - International journal of …, 2023 - mdpi.com
Earlier studies have reported that elevated protein levels in the aqueous humor (AH) are
associated with corneal endothelial cell dysfunction (CECD), but the details of the …

EBD: an eye biomarker database

X Zhang, L Kong, S Liu, X Zhang, X Shang, Z Zhu… - …, 2023 - academic.oup.com
Motivation Many ophthalmic disease biomarkers have been identified through
comprehensive multiomics profiling, and hold significant potential in advancing the …