A causal role for brain-derived neurotrophic factor in the homeostatic regulation of sleep

U Faraguna, VV Vyazovskiy, AB Nelson… - Journal of …, 2008 - Soc Neuroscience
Slow-wave activity (SWA), the EEG power between 0.5 and 4 Hz during non-rapid eye
movement (NREM) sleep, is one of the best characterized markers of sleep need, because it …

Brain-derived neurotrophic factor enhances spontaneous sleep in rats and rabbits

T Kushikata, J Fang… - American Journal of …, 1999 - journals.physiology.org
Various growth factors are involved in sleep regulation. Brain-derived neurotrophic factor
(BDNF) belongs to the neurotrophin family; it and its receptors are found in normal brain …

The brain-derived neurotrophic factor: missing link between sleep deprivation, insomnia, and depression

M Rahmani, F Rahmani, N Rezaei - Neurochemical research, 2020 - Springer
The brain-derived neurotrophic factor (BDNF) mediates the plasticity-related changes that
associate with memory processing during sleep. Sleep deprivation and chronic stress are …

Exploratory behavior, cortical BDNF expression, and sleep homeostasis

R Huber, G Tononi, C Cirelli - Sleep, 2007 - academic.oup.com
Abstract Study Objective: Slow-wave activity (SWA; 0.5–4.0 Hz) during non-rapid eye
movement (NREM) sleep is a reliable indicator of sleep need, as it increases with the …

Peripheral brain-derived neurotrophic factor (BDNF) in insomnia: A systematic review and meta-analysis

A Ballesio, A Zagaria, DG Curti, R Moran… - Sleep medicine …, 2023 - Elsevier
The brain-derived neurotrophic factor (BDNF) is associated with emotional and cognitive
functioning, and it is considered a transdiagnostic biomarker for mental disorders. Literature …

The BDNF Val66Met Polymorphism Modulates Sleep Intensity: EEG Frequency- and State-Specificity

V Bachmann, C Klein, S Bodenmann, N Schaefer… - Sleep, 2012 - academic.oup.com
Study Objectives: EEG slow waves are the hallmark of deep NREM sleep and may reflect
the restorative functions of sleep. Evidence suggests that increased sleep slow waves after …

Chronic sleep restriction elevates brain interleukin-1 beta and tumor necrosis factor-alpha and attenuates brain-derived neurotrophic factor expression

MR Zielinski, Y Kim, SA Karpova, RW McCarley… - Neuroscience …, 2014 - Elsevier
Acute sleep loss increases pro-inflammatory and synaptic plasticity-related molecules in the
brain, including interleukin-1 beta (IL-1β), tumor necrosis factor-alpha (TNF-α), and brain …

Sleep deprivation effects on growth factor expression in neonatal rats: a potential role for BDNF in the mediation of delta power

IS Hairston, C Peyron, DP Denning… - Journal of …, 2004 - journals.physiology.org
The sleeping brain differs from the waking brain in its electrophysiological and molecular
properties, including the expression of growth factors and immediate early genes (IEG) …

Role of brain-derived neurotrophic factor in the circadian regulation of the suprachiasmatic pacemaker by light

FQ Liang, G Allen, D Earnest - Journal of Neuroscience, 2000 - Soc Neuroscience
The central pacemaker located in the suprachiasmatic nucleus (SCN) of the hypothalamus
mediates the generation of mammalian circadian rhythms, including an oscillation in …

BDNF and trkB mRNAs oscillate in rat brain during the light–dark cycle

R Bova, MR Micheli, P Qualadrucci… - Molecular Brain Research, 1998 - Elsevier
In this study, we investigated whether in basal conditions the different functional states
occurring during a 24-h cycle are reflected by the expression of brain-derived neurotrophic …