One of the major obstacles in achieving a successful stem cell therapy is insufficient homing
of transplanted cells. To overcome this obstacle, understanding the underlying mechanisms …

Platelets are primarily known for their contribution to hemostasis and subsequent wound
healing. In addition to these functions, platelets play a role in the process of metastasis …

Cancer-associated mortality is frequently caused by metastasis, however, our understanding
of this process remains incomplete and therapeutic options are limited. Metastasis is a …

The use of stem cells is considered a promising therapy for tissue regeneration and repair,
particularly for tissues injured through degeneration, ischemia and inflammation. Bone …

The high mortality rate of breast cancer is mainly caused by the metastatic ability of cancer
cells, resistance to chemotherapy and radiotherapy, and tumor regression capacity. In recent …

Cancer progress is accompanied by platelet activation and thrombotic complications.
Platelets are a dangerous alliance of cancer cells, and are a close engager in multiple …

Platelets are essential components of hemostasis. Due to a plethora of factors released on
activation, platelet functions are also connected to tumor growth, notably by acting on …

Metastasis is the main cause of cancer-associated mortality. During this complicated
process, some cancer cells, also called circulating tumor cells (CTCs), detach from primary …

Platelets play a crucial role in cancer blood metastasis. Various cancer-related factors such
as Toll-like receptors (TLRs), adenosine diphosphate (ADP) or extracellular matrix (ECM) …

The prometastatic role of platelets has long been recognized with proposed mechanisms of
action including shielding tumor cells from natural killer (NK) cell destruction and aiding …