Feasibility and early clinical impact of precision medicine for late-stage cancer patients in a regional public academic hospital

M Ladekarl, AK Nøhr, M Sønderkær, SC Dahl… - Acta …, 2023 - Taylor & Francis
Aim Our goal was to describe a precision medicine program in a regional academic hospital,
characterize features of included patients and present early data on clinical impact …

A retrospective analysis of precision medicine outcomes in patients with advanced cancer reveals improved progression-free survival without increased health care …

DS Haslem, SB Van Norman, G Fulde… - Journal of oncology …, 2017 - ascopubs.org
Purpose: The advent of genomic diagnostic technologies such as next-generation
sequencing has recently enabled the use of genomic information to guide targeted treatment …

Precision oncology in solid tumors: A longitudinal tertiary care center experience

M Sadaps, P Funchain, H Mahdi, P Grivas… - JCO Precision …, 2018 - ascopubs.org
Purpose Precision oncology is widely discussed, but cohort studies are limited. We
previously reported our prospective experience of precision oncology in solid tumors, and …

Precision medicine to improve survival without increasing costs in advanced cancer patients.

L Nadauld, SB Van Norman, G Fulde, JG McDermott… - 2015 - ascopubs.org
e17641 Background: The advent of Next-Generation Sequencing (NGS), and other
diagnostic technologies, has enabled the use of genomic information to guide targeted …

[HTML][HTML] Precision medicine: preliminary results from the Initiative for Molecular Profiling and Advanced Cancer Therapy 2 (IMPACT2) study

AM Tsimberidou, DS Hong, S Fu, DD Karp… - NPJ Precision …, 2021 - nature.com
Precision medicine is associated with favorable outcomes in selected patients with cancer.
Herein, we report an interim analysis of IMPACT2, an ongoing randomized study evaluating …

[HTML][HTML] Impact of precision medicine in diverse cancers: a meta-analysis of phase II clinical trials

M Schwaederle, M Zhao, JJ Lee… - Journal of clinical …, 2015 - ncbi.nlm.nih.gov
Purpose The impact of a personalized cancer treatment strategy (ie, matching patients with
drugs based on specific biomarkers) is still a matter of debate. Methods We reviewed phase …

Individualized molecular profiling for allocation to clinical trials Singapore study—An Asian tertiary cancer center experience

AOL Seet, AC Tan, TJ Tan, MCH Ng, DWM Tai… - JCO Precision …, 2021 - ascopubs.org
PURPOSE Precision oncology has transformed the management of advanced cancers
through implementation of advanced molecular profiling technologies to identify increasingly …

Widespread adoption of precision anticancer therapies after implementation of pathologist-directed comprehensive genomic profiling across a large US health system

AK Dowdell, R Meng, A Vita, B Bapat, D Hanes… - medRxiv, 2024 - medrxiv.org
Precision therapies and immunotherapies have revolutionized cancer care, resulting in
significant gains in patient survival across tumor types. Despite this transformation in care …

IMPRESS-Norway: Improving public cancer care by implementing precision cancer medicine in Norway.

A Helland, S Smeland, H Russnes, S Brabrand, K Puco… - 2023 - ascopubs.org
e15188 Background: Precision cancer medicine is evolving rapidly, with new drugs and
biomarkers being developed. Advanced molecular diagnostics is a prerequisite for using …

Improved outcomes from reflex comprehensive genomic profiling-guided precision therapeutic selection across a major US healthcare system.

B Piening, B Bapat, RK Weerasinghe, R Meng… - 2023 - ascopubs.org
6622 Background: An ever-increasing number of biomarker-guided therapies, some with
pan-cancer indications have expanded the oncologist's toolbox for fighting advanced …