Feasibility and early clinical impact of precision medicine for late-stage cancer patients in a regional public academic hospital
M Ladekarl, AK Nøhr, M Sønderkær, SC Dahl… - Acta …, 2023 - Taylor & Francis
Aim Our goal was to describe a precision medicine program in a regional academic hospital,
characterize features of included patients and present early data on clinical impact …
characterize features of included patients and present early data on clinical impact …
A retrospective analysis of precision medicine outcomes in patients with advanced cancer reveals improved progression-free survival without increased health care …
DS Haslem, SB Van Norman, G Fulde… - Journal of oncology …, 2017 - ascopubs.org
Purpose: The advent of genomic diagnostic technologies such as next-generation
sequencing has recently enabled the use of genomic information to guide targeted treatment …
sequencing has recently enabled the use of genomic information to guide targeted treatment …
Precision oncology in solid tumors: A longitudinal tertiary care center experience
Purpose Precision oncology is widely discussed, but cohort studies are limited. We
previously reported our prospective experience of precision oncology in solid tumors, and …
previously reported our prospective experience of precision oncology in solid tumors, and …
Precision medicine to improve survival without increasing costs in advanced cancer patients.
L Nadauld, SB Van Norman, G Fulde, JG McDermott… - 2015 - ascopubs.org
e17641 Background: The advent of Next-Generation Sequencing (NGS), and other
diagnostic technologies, has enabled the use of genomic information to guide targeted …
diagnostic technologies, has enabled the use of genomic information to guide targeted …
[HTML][HTML] Precision medicine: preliminary results from the Initiative for Molecular Profiling and Advanced Cancer Therapy 2 (IMPACT2) study
AM Tsimberidou, DS Hong, S Fu, DD Karp… - NPJ Precision …, 2021 - nature.com
Precision medicine is associated with favorable outcomes in selected patients with cancer.
Herein, we report an interim analysis of IMPACT2, an ongoing randomized study evaluating …
Herein, we report an interim analysis of IMPACT2, an ongoing randomized study evaluating …
[HTML][HTML] Impact of precision medicine in diverse cancers: a meta-analysis of phase II clinical trials
M Schwaederle, M Zhao, JJ Lee… - Journal of clinical …, 2015 - ncbi.nlm.nih.gov
Purpose The impact of a personalized cancer treatment strategy (ie, matching patients with
drugs based on specific biomarkers) is still a matter of debate. Methods We reviewed phase …
drugs based on specific biomarkers) is still a matter of debate. Methods We reviewed phase …
Individualized molecular profiling for allocation to clinical trials Singapore study—An Asian tertiary cancer center experience
PURPOSE Precision oncology has transformed the management of advanced cancers
through implementation of advanced molecular profiling technologies to identify increasingly …
through implementation of advanced molecular profiling technologies to identify increasingly …
Widespread adoption of precision anticancer therapies after implementation of pathologist-directed comprehensive genomic profiling across a large US health system
AK Dowdell, R Meng, A Vita, B Bapat, D Hanes… - medRxiv, 2024 - medrxiv.org
Precision therapies and immunotherapies have revolutionized cancer care, resulting in
significant gains in patient survival across tumor types. Despite this transformation in care …
significant gains in patient survival across tumor types. Despite this transformation in care …
IMPRESS-Norway: Improving public cancer care by implementing precision cancer medicine in Norway.
A Helland, S Smeland, H Russnes, S Brabrand, K Puco… - 2023 - ascopubs.org
e15188 Background: Precision cancer medicine is evolving rapidly, with new drugs and
biomarkers being developed. Advanced molecular diagnostics is a prerequisite for using …
biomarkers being developed. Advanced molecular diagnostics is a prerequisite for using …
Improved outcomes from reflex comprehensive genomic profiling-guided precision therapeutic selection across a major US healthcare system.
6622 Background: An ever-increasing number of biomarker-guided therapies, some with
pan-cancer indications have expanded the oncologist's toolbox for fighting advanced …
pan-cancer indications have expanded the oncologist's toolbox for fighting advanced …