Covalent modifications of histones can regulate all DNA-dependent processes. In the last
few years, it has become more and more evident that histone modifications are key players …

Histones are DNA‐binding basic proteins found in chromosomes. After the histone
translation, its amino tail undergoes various modifications, such as methylation, acetylation …

Histone posttranslational modifications represent a versatile set of epigenetic marks
involved not only in dynamic cellular processes, such as transcription and DNA repair, but …

In all organisms, cell proliferation is orchestrated by coordinated patterns of gene
expression. Transcription results from the activity of the RNA polymerase machinery and …

Histone post-translational modifications (PTMs) have emerged as exciting mechanisms of
biological regulation, impacting pathways related to cancer, immunity, brain function, and …

Post-translational modification of histones provides an important regulatory platform for
processes such as gene expression, DNA replication and repair, chromosome condensation …

Histone modifications are key factors in chromatin packaging, and are responsible for gene
regulation during cell fate determination and development. Abnormal alterations in histone …

Histone posttranslational modifications (HPTMs) are crucial epigenetic mechanisms
regulating various biological events. Different types of HPTMs characterize and shape …

Global alterations in epigenetic landscape are now recognized as a hallmark of cancer.
Epigenetic mechanisms such as DNA methylation, histone modifications, nucleosome …

The epigenetic modifications of histones are versatile marks that are intimately connected to
development and disease pathogenesis including human cancers. In this review, we will …